LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 CGP60474
0.12
uM
LJP6
 1
G05
 72
hr
 868 775 3429 0.2260 -0.0556
MDA-MB-231 CGP60474
0.12
uM
LJP6
 2
G05
 72
hr
 868 861 3652 0.2358 -0.0040
MDA-MB-231 CGP60474
0.12
uM
LJP6
 3
G05
 72
hr
 868 854 3587 0.2381 -0.0080
MDA-MB-231 CGP60474
0.12
uM
LJP5
 1
F05
 72
hr
 868 950 3286 0.2891 0.0481
MDA-MB-231 CGP60474
0.12
uM
LJP5
 2
F05
 72
hr
 868 903 3505 0.2576 0.0198
MDA-MB-231 CGP60474
0.12
uM
LJP5
 3
F05
 72
hr
 868 986 3440 0.2866 0.0662
MDA-MB-231 CGP60474
0.37
uM
LJP6
 1
G04
 72
hr
 868 824 3429 0.2403 -0.0260
MDA-MB-231 CGP60474
0.37
uM
LJP6
 2
G04
 72
hr
 868 835 3652 0.2286 -0.0186
MDA-MB-231 CGP60474
0.37
uM
LJP6
 3
G04
 72
hr
 868 765 3587 0.2133 -0.0599
MDA-MB-231 CGP60474
0.37
uM
LJP5
 1
F04
 72
hr
 868 717 3286 0.2182 -0.0948
MDA-MB-231 CGP60474
0.37
uM
LJP5
 2
F04
 72
hr
 868 622 3505 0.1774 -0.1526
MDA-MB-231 CGP60474
0.37
uM
LJP5
 3
F04
 72
hr
 868 748 3440 0.2174 -0.0722
MDA-MB-231 CGP60474
1.11
uM
LJP6
 1
G03
 72
hr
 868 625 3429 0.1822 -0.1528
MDA-MB-231 CGP60474
1.11
uM
LJP6
 2
G03
 72
hr
 868 554 3652 0.1517 -0.1948
MDA-MB-231 CGP60474
1.11
uM
LJP6
 3
G03
 72
hr
 868 685 3587 0.1910 -0.1093
MDA-MB-231 CGP60474
1.11
uM
LJP5
 1
F03
 72
hr
 868 652 3286 0.1984 -0.1385
MDA-MB-231 CGP60474
1.11
uM
LJP5
 2
F03
 72
hr
 868 613 3505 0.1749 -0.1587
MDA-MB-231 CGP60474
1.11
uM
LJP5
 3
F03
 72
hr
 868 723 3440 0.2102 -0.0880
MDA-MB-231 CGP60474
3.33
uM
LJP6
 1
G02
 72
hr
 868 486 3429 0.1417 -0.2537
MDA-MB-231 CGP60474
3.33
uM
LJP6
 2
G02
 72
hr
 868 500 3652 0.1369 -0.2337
MDA-MB-231 CGP60474
3.33
uM
LJP6
 3
G02
 72
hr
 868 595 3587 0.1659 -0.1685
MDA-MB-231 CGP60474
3.33
uM
LJP5
 1
F02
 72
hr
 868 575 3286 0.1750 -0.1931
MDA-MB-231 CGP60474
3.33
uM
LJP5
 2
F02
 72
hr
 868 644 3505 0.1837 -0.1378
MDA-MB-231 CGP60474
3.33
uM
LJP5
 3
F02
 72
hr
 868 676 3440 0.1965 -0.1183
MDA-MB-231 CGP60474
10
uM
LJP6
 1
G01
 72
hr
 868 366 3429 0.1067 -0.3532