LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Gefitinib
0.04
uM
LJP6
 1
N12
 72
hr
 868 3985 3429 1.1619 1.1573
MDA-MB-231 Gefitinib
0.04
uM
LJP6
 2
N12
 72
hr
 868 4155 3652 1.1377 1.1285
MDA-MB-231 Gefitinib
0.04
uM
LJP6
 3
N12
 72
hr
 868 4060 3587 1.1318 1.1247
MDA-MB-231 Gefitinib
0.12
uM
LJP6
 1
N11
 72
hr
 868 3634 3429 1.0595 1.0592
MDA-MB-231 Gefitinib
0.12
uM
LJP6
 2
N11
 72
hr
 868 4003 3652 1.0961 1.0905
MDA-MB-231 Gefitinib
0.12
uM
LJP6
 3
N11
 72
hr
 868 4165 3587 1.1610 1.1514
MDA-MB-231 Gefitinib
0.37
uM
LJP6
 1
N10
 72
hr
 868 3516 3429 1.0251 1.0252
MDA-MB-231 Gefitinib
0.37
uM
LJP6
 2
N10
 72
hr
 868 3790 3652 1.0378 1.0361
MDA-MB-231 Gefitinib
0.37
uM
LJP6
 3
N10
 72
hr
 868 3699 3587 1.0311 1.0302
MDA-MB-231 Gefitinib
1.11
uM
LJP6
 1
N09
 72
hr
 868 3614 3429 1.0537 1.0535
MDA-MB-231 Gefitinib
1.11
uM
LJP6
 2
N09
 72
hr
 868 3769 3652 1.0320 1.0307
MDA-MB-231 Gefitinib
1.11
uM
LJP6
 3
N09
 72
hr
 868 3990 3587 1.1123 1.1067
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 1
N08
 72
hr
 868 3614 3429 1.0537 1.0535
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 2
N08
 72
hr
 868 3948 3652 1.0811 1.0766
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 3
N08
 72
hr
 868 3982 3587 1.1100 1.1046
MDA-MB-231 Gefitinib
10
uM
LJP6
 1
N07
 72
hr
 868 3036 3429 0.8852 0.8807
MDA-MB-231 Gefitinib
10
uM
LJP6
 2
N07
 72
hr
 868 3294 3652 0.9020 0.9029
MDA-MB-231 Gefitinib
10
uM
LJP6
 3
N07
 72
hr
 868 3123 3587 0.8706 0.8691
MDA-MB-231 Nilotinib
0.04
uM
LJP5
 1
N18
 72
hr
 868 2890 3286 0.8794 0.8706
MDA-MB-231 Nilotinib
0.04
uM
LJP5
 2
N18
 72
hr
 868 3201 3505 0.9132 0.9118
MDA-MB-231 Nilotinib
0.04
uM
LJP5
 3
N18
 72
hr
 868 3201 3440 0.9305 0.9287
MDA-MB-231 Nilotinib
0.12
uM
LJP5
 1
N17
 72
hr
 868 2580 3286 0.7851 0.7632
MDA-MB-231 Nilotinib
0.12
uM
LJP5
 2
N17
 72
hr
 868 2806 3505 0.8005 0.7907
MDA-MB-231 Nilotinib
0.12
uM
LJP5
 3
N17
 72
hr
 868 2971 3440 0.8636 0.8577
MDA-MB-231 Nilotinib
0.37
uM
LJP5
 1
N16
 72
hr
 868 2433 3286 0.7404 0.7102