LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 XMD16-144
1.11
uM
LJP5
 3
M09
 72
hr
 868 1309 3440 0.3805 0.2297
MDA-MB-231 XMD16-144
3.33
uM
LJP5
 1
M08
 72
hr
 868 1172 3286 0.3566 0.1692
MDA-MB-231 XMD16-144
3.33
uM
LJP5
 2
M08
 72
hr
 868 1362 3505 0.3885 0.2507
MDA-MB-231 XMD16-144
3.33
uM
LJP5
 3
M08
 72
hr
 868 1221 3440 0.3549 0.1873
MDA-MB-231 XMD16-144
10
uM
LJP5
 1
M07
 72
hr
 868 820 3286 0.2495 -0.0293
MDA-MB-231 XMD16-144
10
uM
LJP5
 2
M07
 72
hr
 868 996 3505 0.2841 0.0706
MDA-MB-231 XMD16-144
10
uM
LJP5
 3
M07
 72
hr
 868 958 3440 0.2785 0.0508
MDA-MB-231 Erlotinib
0.04
uM
LJP5
 1
M24
 72
hr
 868 2627 3286 0.7994 0.7799
MDA-MB-231 Erlotinib
0.04
uM
LJP5
 2
M24
 72
hr
 868 3236 3505 0.9231 0.9221
MDA-MB-231 Erlotinib
0.04
uM
LJP5
 3
M24
 72
hr
 868 2842 3440 0.8261 0.8166
MDA-MB-231 Erlotinib
0.12
uM
LJP5
 1
M23
 72
hr
 868 3218 3286 0.9792 0.9783
MDA-MB-231 Erlotinib
0.12
uM
LJP5
 2
M23
 72
hr
 868 3145 3505 0.8972 0.8951
MDA-MB-231 Erlotinib
0.12
uM
LJP5
 3
M23
 72
hr
 868 3160 3440 0.9185 0.9163
MDA-MB-231 Erlotinib
0.37
uM
LJP5
 1
M22
 72
hr
 868 3017 3286 0.9181 0.9129
MDA-MB-231 Erlotinib
0.37
uM
LJP5
 2
M22
 72
hr
 868 3457 3505 0.9862 0.9862
MDA-MB-231 Erlotinib
0.37
uM
LJP5
 3
M22
 72
hr
 868 3305 3440 0.9607 0.9600
MDA-MB-231 Erlotinib
1.11
uM
LJP5
 1
M21
 72
hr
 868 3325 3286 1.0118 1.0122
MDA-MB-231 Erlotinib
1.11
uM
LJP5
 2
M21
 72
hr
 868 3533 3505 1.0079 1.0078
MDA-MB-231 Erlotinib
1.11
uM
LJP5
 3
M21
 72
hr
 868 3158 3440 0.9180 0.9156
MDA-MB-231 Erlotinib
3.33
uM
LJP5
 1
M20
 72
hr
 868 3212 3286 0.9774 0.9763
MDA-MB-231 Erlotinib
3.33
uM
LJP5
 2
M20
 72
hr
 868 3565 3505 1.0170 1.0168
MDA-MB-231 Erlotinib
3.33
uM
LJP5
 3
M20
 72
hr
 868 3291 3440 0.9566 0.9558
MDA-MB-231 Erlotinib
10
uM
LJP5
 1
M19
 72
hr
 868 2014 3286 0.6129 0.5499
MDA-MB-231 Erlotinib
10
uM
LJP5
 2
M19
 72
hr
 868 2315 3505 0.6604 0.6276
MDA-MB-231 Erlotinib
10
uM
LJP5
 3
M19
 72
hr
 868 1995 3440 0.5799 0.5202