LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 SU11274
10
uM
LJP5
 2
J07
 72
hr
 868 1289 3505 0.3677 0.2169
MDA-MB-231 SU11274
10
uM
LJP5
 3
J07
 72
hr
 868 1269 3440 0.3689 0.2106
MDA-MB-231 Canertinib
0.04
uM
LJP6
 1
H12
 72
hr
 868 3518 3429 1.0257 1.0258
MDA-MB-231 Canertinib
0.04
uM
LJP6
 2
H12
 72
hr
 868 3910 3652 1.0706 1.0670
MDA-MB-231 Canertinib
0.04
uM
LJP6
 3
H12
 72
hr
 868 4066 3587 1.1334 1.1262
MDA-MB-231 Canertinib
0.12
uM
LJP6
 1
H11
 72
hr
 868 3084 3429 0.8992 0.8956
MDA-MB-231 Canertinib
0.12
uM
LJP6
 2
H11
 72
hr
 868 3660 3652 1.0022 1.0021
MDA-MB-231 Canertinib
0.12
uM
LJP6
 3
H11
 72
hr
 868 3407 3587 0.9497 0.9503
MDA-MB-231 Canertinib
0.37
uM
LJP6
 1
H10
 72
hr
 868 2923 3429 0.8522 0.8450
MDA-MB-231 Canertinib
0.37
uM
LJP6
 2
H10
 72
hr
 868 3358 3652 0.9195 0.9206
MDA-MB-231 Canertinib
0.37
uM
LJP6
 3
H10
 72
hr
 868 3206 3587 0.8937 0.8932
MDA-MB-231 Canertinib
1.11
uM
LJP6
 1
H09
 72
hr
 868 2406 3429 0.7015 0.6724
MDA-MB-231 Canertinib
1.11
uM
LJP6
 2
H09
 72
hr
 868 3067 3652 0.8398 0.8385
MDA-MB-231 Canertinib
1.11
uM
LJP6
 3
H09
 72
hr
 868 2988 3587 0.8329 0.8291
MDA-MB-231 Canertinib
3.33
uM
LJP6
 1
H08
 72
hr
 868 1958 3429 0.5709 0.5073
MDA-MB-231 Canertinib
3.33
uM
LJP6
 2
H08
 72
hr
 868 2546 3652 0.6972 0.6805
MDA-MB-231 Canertinib
3.33
uM
LJP6
 3
H08
 72
hr
 868 2411 3587 0.6721 0.6471
MDA-MB-231 Canertinib
10
uM
LJP6
 1
H07
 72
hr
 868 420 3429 0.1225 -0.3067
MDA-MB-231 Canertinib
10
uM
LJP6
 2
H07
 72
hr
 868 734 3652 0.2010 -0.0778
MDA-MB-231 Canertinib
10
uM
LJP6
 3
H07
 72
hr
 868 699 3587 0.1949 -0.1005
MDA-MB-231 NVP-AEW541
0.04
uM
LJP5
 1
E18
 72
hr
 868 3664 3286 1.1149 1.1166
MDA-MB-231 NVP-AEW541
0.04
uM
LJP5
 2
E18
 72
hr
 868 3351 3505 0.9560 0.9558
MDA-MB-231 NVP-AEW541
0.04
uM
LJP5
 3
E18
 72
hr
 868 3580 3440 1.0406 1.0405
MDA-MB-231 NVP-AEW541
0.12
uM
LJP5
 1
E17
 72
hr
 868 3555 3286 1.0818 1.0835
MDA-MB-231 NVP-AEW541
0.12
uM
LJP5
 2
E17
 72
hr
 868 3305 3505 0.9428 0.9424