LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 NVP-AEW541
0.12
uM
LJP5
 3
E17
 72
hr
 868 3651 3440 1.0612 1.0608
MDA-MB-231 NVP-AEW541
0.37
uM
LJP5
 1
E16
 72
hr
 868 3622 3286 1.1022 1.1039
MDA-MB-231 NVP-AEW541
0.37
uM
LJP5
 2
E16
 72
hr
 868 3251 3505 0.9274 0.9265
MDA-MB-231 NVP-AEW541
0.37
uM
LJP5
 3
E16
 72
hr
 868 3876 3440 1.1267 1.1237
MDA-MB-231 NVP-AEW541
1.11
uM
LJP5
 1
E15
 72
hr
 868 3544 3286 1.0784 1.0802
MDA-MB-231 NVP-AEW541
1.11
uM
LJP5
 2
E15
 72
hr
 868 3436 3505 0.9802 0.9802
MDA-MB-231 NVP-AEW541
1.11
uM
LJP5
 3
E15
 72
hr
 868 3252 3440 0.9453 0.9441
MDA-MB-231 NVP-AEW541
3.33
uM
LJP5
 1
E14
 72
hr
 868 3413 3286 1.0386 1.0398
MDA-MB-231 NVP-AEW541
3.33
uM
LJP5
 2
E14
 72
hr
 868 3340 3505 0.9528 0.9526
MDA-MB-231 NVP-AEW541
3.33
uM
LJP5
 3
E14
 72
hr
 868 3387 3440 0.9845 0.9844
MDA-MB-231 NVP-AEW541
10
uM
LJP5
 1
E13
 72
hr
 868 1418 3286 0.4315 0.2911
MDA-MB-231 NVP-AEW541
10
uM
LJP5
 2
E13
 72
hr
 868 1160 3505 0.3309 0.1548
MDA-MB-231 NVP-AEW541
10
uM
LJP5
 3
E13
 72
hr
 868 1444 3440 0.4197 0.2919
MDA-MB-231 PHA-665752
0.04
uM
LJP5
 1
F18
 72
hr
 868 3521 3286 1.0714 1.0731
MDA-MB-231 PHA-665752
0.04
uM
LJP5
 2
F18
 72
hr
 868 3440 3505 0.9813 0.9814
MDA-MB-231 PHA-665752
0.04
uM
LJP5
 3
F18
 72
hr
 868 3799 3440 1.1043 1.1024
MDA-MB-231 PHA-665752
0.12
uM
LJP5
 1
F17
 72
hr
 868 3918 3286 1.1922 1.1917
MDA-MB-231 PHA-665752
0.12
uM
LJP5
 2
F17
 72
hr
 868 3440 3505 0.9813 0.9814
MDA-MB-231 PHA-665752
0.12
uM
LJP5
 3
F17
 72
hr
 868 3905 3440 1.1351 1.1317
MDA-MB-231 PHA-665752
0.37
uM
LJP5
 1
F16
 72
hr
 868 3581 3286 1.0897 1.0915
MDA-MB-231 PHA-665752
0.37
uM
LJP5
 2
F16
 72
hr
 868 3533 3505 1.0079 1.0078
MDA-MB-231 PHA-665752
0.37
uM
LJP5
 3
F16
 72
hr
 868 3806 3440 1.1063 1.1043
MDA-MB-231 PHA-665752
1.11
uM
LJP5
 1
F15
 72
hr
 868 3596 3286 1.0942 1.0960
MDA-MB-231 PHA-665752
1.11
uM
LJP5
 2
F15
 72
hr
 868 3232 3505 0.9220 0.9209
MDA-MB-231 PHA-665752
1.11
uM
LJP5
 3
F15
 72
hr
 868 3904 3440 1.1348 1.1314