LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Buparlisib
0.12
uM
LJP5
 1
H05
 72
hr
 868 3356 3286 1.0212 1.0220
MDA-MB-231 Buparlisib
0.12
uM
LJP5
 2
H05
 72
hr
 868 3442 3505 0.9819 0.9820
MDA-MB-231 Buparlisib
0.12
uM
LJP5
 3
H05
 72
hr
 868 3479 3440 1.0113 1.0113
MDA-MB-231 Buparlisib
0.37
uM
LJP5
 1
H04
 72
hr
 868 2633 3286 0.8012 0.7820
MDA-MB-231 Buparlisib
0.37
uM
LJP5
 2
H04
 72
hr
 868 2776 3505 0.7919 0.7812
MDA-MB-231 Buparlisib
0.37
uM
LJP5
 3
H04
 72
hr
 868 2964 3440 0.8616 0.8555
MDA-MB-231 Buparlisib
1.11
uM
LJP5
 1
H03
 72
hr
 868 1802 3286 0.5483 0.4627
MDA-MB-231 Buparlisib
1.11
uM
LJP5
 2
H03
 72
hr
 868 1832 3505 0.5226 0.4490
MDA-MB-231 Buparlisib
1.11
uM
LJP5
 3
H03
 72
hr
 868 1705 3440 0.4956 0.4046
MDA-MB-231 Buparlisib
3.33
uM
LJP5
 1
H02
 72
hr
 868 1139 3286 0.3466 0.1519
MDA-MB-231 Buparlisib
3.33
uM
LJP5
 2
H02
 72
hr
 868 1072 3505 0.3058 0.1105
MDA-MB-231 Buparlisib
3.33
uM
LJP5
 3
H02
 72
hr
 868 1195 3440 0.3474 0.1745
MDA-MB-231 Buparlisib
10
uM
LJP5
 1
H01
 72
hr
 868 575 3286 0.1750 -0.1931
MDA-MB-231 Buparlisib
10
uM
LJP5
 2
H01
 72
hr
 868 692 3505 0.1974 -0.1065
MDA-MB-231 Buparlisib
10
uM
LJP5
 3
H01
 72
hr
 868 716 3440 0.2081 -0.0924
MDA-MB-231 XL147
0.04
uM
LJP5
 1
G12
 72
hr
 868 3899 3286 1.1864 1.1862
MDA-MB-231 XL147
0.04
uM
LJP5
 2
G12
 72
hr
 868 3809 3505 1.0866 1.0842
MDA-MB-231 XL147
0.04
uM
LJP5
 3
G12
 72
hr
 868 3540 3440 1.0290 1.0290
MDA-MB-231 XL147
0.12
uM
LJP5
 1
G11
 72
hr
 868 3546 3286 1.0790 1.0808
MDA-MB-231 XL147
0.12
uM
LJP5
 2
G11
 72
hr
 868 3726 3505 1.0629 1.0615
MDA-MB-231 XL147
0.12
uM
LJP5
 3
G11
 72
hr
 868 3743 3440 1.0880 1.0867
MDA-MB-231 XL147
0.37
uM
LJP5
 1
G10
 72
hr
 868 3608 3286 1.0979 1.0997
MDA-MB-231 XL147
0.37
uM
LJP5
 2
G10
 72
hr
 868 3689 3505 1.0524 1.0513
MDA-MB-231 XL147
0.37
uM
LJP5
 3
G10
 72
hr
 868 3682 3440 1.0703 1.0695
MDA-MB-231 XL147
1.11
uM
LJP5
 1
G09
 72
hr
 868 3887 3286 1.1828 1.1827