LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 XL147
1.11
uM
LJP5
 2
G09
 72
hr
 868 3837 3505 1.0946 1.0918
MDA-MB-231 XL147
1.11
uM
LJP5
 3
G09
 72
hr
 868 3692 3440 1.0732 1.0724
MDA-MB-231 XL147
3.33
uM
LJP5
 1
G08
 72
hr
 868 3545 3286 1.0787 1.0805
MDA-MB-231 XL147
3.33
uM
LJP5
 2
G08
 72
hr
 868 3541 3505 1.0101 1.0101
MDA-MB-231 XL147
3.33
uM
LJP5
 3
G08
 72
hr
 868 3748 3440 1.0894 1.0881
MDA-MB-231 XL147
10
uM
LJP5
 1
G07
 72
hr
 868 3387 3286 1.0306 1.0317
MDA-MB-231 XL147
10
uM
LJP5
 2
G07
 72
hr
 868 3341 3505 0.9531 0.9529
MDA-MB-231 XL147
10
uM
LJP5
 3
G07
 72
hr
 868 3222 3440 0.9366 0.9351
MDA-MB-231 Y39983
0.04
uM
LJP6
 1
P06
 72
hr
 868 2642 3429 0.7703 0.7533
MDA-MB-231 Y39983
0.04
uM
LJP6
 2
P06
 72
hr
 868 3518 3652 0.9633 0.9643
MDA-MB-231 Y39983
0.04
uM
LJP6
 3
P06
 72
hr
 868 3554 3587 0.9907 0.9909
MDA-MB-231 Y39983
0.12
uM
LJP6
 1
P05
 72
hr
 868 2677 3429 0.7805 0.7650
MDA-MB-231 Y39983
0.12
uM
LJP6
 2
P05
 72
hr
 868 3417 3652 0.9357 0.9368
MDA-MB-231 Y39983
0.12
uM
LJP6
 3
P05
 72
hr
 868 3198 3587 0.8915 0.8909
MDA-MB-231 Y39983
0.37
uM
LJP6
 1
P04
 72
hr
 868 2402 3429 0.7003 0.6710
MDA-MB-231 Y39983
0.37
uM
LJP6
 2
P04
 72
hr
 868 3045 3652 0.8338 0.8321
MDA-MB-231 Y39983
0.37
uM
LJP6
 3
P04
 72
hr
 868 3098 3587 0.8636 0.8617
MDA-MB-231 Y39983
1.11
uM
LJP6
 1
P03
 72
hr
 868 2286 3429 0.6665 0.6298
MDA-MB-231 Y39983
1.11
uM
LJP6
 2
P03
 72
hr
 868 2686 3652 0.7355 0.7245
MDA-MB-231 Y39983
1.11
uM
LJP6
 3
P03
 72
hr
 868 2686 3587 0.7488 0.7364
MDA-MB-231 Y39983
3.33
uM
LJP6
 1
P02
 72
hr
 868 1823 3429 0.5315 0.4540
MDA-MB-231 Y39983
3.33
uM
LJP6
 2
P02
 72
hr
 868 2362 3652 0.6468 0.6208
MDA-MB-231 Y39983
3.33
uM
LJP6
 3
P02
 72
hr
 868 2039 3587 0.5684 0.5176
MDA-MB-231 Y39983
10
uM
LJP6
 1
P01
 72
hr
 868 545 3429 0.1589 -0.2093
MDA-MB-231 Y39983
10
uM
LJP6
 2
P01
 72
hr
 868 600 3652 0.1643 -0.1632