LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 JNK-9L
3.33
uM
LJP6
 3
K20
 72
hr
 868 895 3587 0.2495 0.0150
MDA-MB-231 JNK-9L
10
uM
LJP6
 1
K19
 72
hr
 868 780 3429 0.2274 -0.0526
MDA-MB-231 JNK-9L
10
uM
LJP6
 2
K19
 72
hr
 868 862 3652 0.2360 -0.0034
MDA-MB-231 JNK-9L
10
uM
LJP6
 3
K19
 72
hr
 868 851 3587 0.2372 -0.0097
MDA-MB-231 PD0325901
0.04
uM
LJP6
 1
E06
 72
hr
 868 1922 3429 0.5604 0.4933
MDA-MB-231 PD0325901
0.04
uM
LJP6
 2
E06
 72
hr
 868 2293 3652 0.6279 0.5978
MDA-MB-231 PD0325901
0.04
uM
LJP6
 3
E06
 72
hr
 868 2397 3587 0.6682 0.6424
MDA-MB-231 PD0325901
0.04
uM
LJP5
 1
C06
 72
hr
 868 2068 3286 0.6293 0.5714
MDA-MB-231 PD0325901
0.04
uM
LJP5
 2
C06
 72
hr
 868 2184 3505 0.6230 0.5812
MDA-MB-231 PD0325901
0.04
uM
LJP5
 3
C06
 72
hr
 868 2118 3440 0.6157 0.5667
MDA-MB-231 PD0325901
0.12
uM
LJP6
 1
E05
 72
hr
 868 1815 3429 0.5292 0.4507
MDA-MB-231 PD0325901
0.12
uM
LJP6
 2
E05
 72
hr
 868 1638 3652 0.4485 0.3584
MDA-MB-231 PD0325901
0.12
uM
LJP6
 3
E05
 72
hr
 868 1809 3587 0.5043 0.4314
MDA-MB-231 PD0325901
0.12
uM
LJP5
 1
C05
 72
hr
 868 1636 3286 0.4978 0.3909
MDA-MB-231 PD0325901
0.12
uM
LJP5
 2
C05
 72
hr
 868 1854 3505 0.5289 0.4576
MDA-MB-231 PD0325901
0.12
uM
LJP5
 3
C05
 72
hr
 868 1694 3440 0.4924 0.4001
MDA-MB-231 PD0325901
0.37
uM
LJP6
 1
E04
 72
hr
 868 1314 3429 0.3831 0.2326
MDA-MB-231 PD0325901
0.37
uM
LJP6
 2
E04
 72
hr
 868 1496 3652 0.4096 0.3003
MDA-MB-231 PD0325901
0.37
uM
LJP6
 3
E04
 72
hr
 868 1344 3587 0.3747 0.2380
MDA-MB-231 PD0325901
0.37
uM
LJP5
 1
C04
 72
hr
 868 1456 3286 0.4431 0.3090
MDA-MB-231 PD0325901
0.37
uM
LJP5
 2
C04
 72
hr
 868 1668 3505 0.4758 0.3831
MDA-MB-231 PD0325901
0.37
uM
LJP5
 3
C04
 72
hr
 868 1295 3440 0.3764 0.2230
MDA-MB-231 PD0325901
1.11
uM
LJP6
 1
E03
 72
hr
 868 972 3429 0.2834 0.0587
MDA-MB-231 PD0325901
1.11
uM
LJP6
 2
E03
 72
hr
 868 1037 3652 0.2840 0.0895
MDA-MB-231 PD0325901
1.11
uM
LJP6
 3
E03
 72
hr
 868 1051 3587 0.2930 0.0979