LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 PD0325901
1.11
uM
LJP5
 1
C03
 72
hr
 868 1224 3286 0.3725 0.1959
MDA-MB-231 PD0325901
1.11
uM
LJP5
 2
C03
 72
hr
 868 1176 3505 0.3355 0.1627
MDA-MB-231 PD0325901
1.11
uM
LJP5
 3
C03
 72
hr
 868 1306 3440 0.3796 0.2282
MDA-MB-231 PD0325901
3.33
uM
LJP6
 1
E02
 72
hr
 868 787 3429 0.2295 -0.0483
MDA-MB-231 PD0325901
3.33
uM
LJP6
 2
E02
 72
hr
 868 838 3652 0.2295 -0.0169
MDA-MB-231 PD0325901
3.33
uM
LJP6
 3
E02
 72
hr
 868 960 3587 0.2676 0.0504
MDA-MB-231 PD0325901
3.33
uM
LJP5
 1
C02
 72
hr
 868 786 3286 0.2392 -0.0504
MDA-MB-231 PD0325901
3.33
uM
LJP5
 2
C02
 72
hr
 868 907 3505 0.2587 0.0220
MDA-MB-231 PD0325901
3.33
uM
LJP5
 3
C02
 72
hr
 868 1130 3440 0.3285 0.1419
MDA-MB-231 PD0325901
10
uM
LJP6
 1
E01
 72
hr
 868 762 3429 0.2222 -0.0637
MDA-MB-231 PD0325901
10
uM
LJP6
 2
E01
 72
hr
 868 740 3652 0.2026 -0.0741
MDA-MB-231 PD0325901
10
uM
LJP6
 3
E01
 72
hr
 868 978 3587 0.2726 0.0600
MDA-MB-231 PD0325901
10
uM
LJP5
 1
C01
 72
hr
 868 832 3286 0.2532 -0.0219
MDA-MB-231 PD0325901
10
uM
LJP5
 2
C01
 72
hr
 868 932 3505 0.2659 0.0359
MDA-MB-231 PD0325901
10
uM
LJP5
 3
C01
 72
hr
 868 930 3440 0.2703 0.0353
MDA-MB-231 Geldanamycin
0.04
uM
LJP6
 1
O06
 72
hr
 868 1575 3429 0.4592 0.3506
MDA-MB-231 Geldanamycin
0.04
uM
LJP6
 2
O06
 72
hr
 868 1534 3652 0.4200 0.3161
MDA-MB-231 Geldanamycin
0.04
uM
LJP6
 3
O06
 72
hr
 868 1810 3587 0.5046 0.4318
MDA-MB-231 Geldanamycin
0.04
uM
LJP5
 1
O06
 72
hr
 868 1176 3286 0.3579 0.1712
MDA-MB-231 Geldanamycin
0.04
uM
LJP5
 2
O06
 72
hr
 868 1419 3505 0.4048 0.2764
MDA-MB-231 Geldanamycin
0.04
uM
LJP5
 3
O06
 72
hr
 868 1344 3440 0.3907 0.2461
MDA-MB-231 Geldanamycin
0.12
uM
LJP6
 1
O05
 72
hr
 868 1152 3429 0.3359 0.1534
MDA-MB-231 Geldanamycin
0.12
uM
LJP6
 2
O05
 72
hr
 868 1259 3652 0.3447 0.1964
MDA-MB-231 Geldanamycin
0.12
uM
LJP6
 3
O05
 72
hr
 868 1270 3587 0.3540 0.2043
MDA-MB-231 Geldanamycin
0.12
uM
LJP5
 1
O05
 72
hr
 868 1065 3286 0.3241 0.1123