LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 QL-X-138
0.12
uM
LJP6
 3
F23
 72
hr
 868 2827 3587 0.7881 0.7803
MDA-MB-231 QL-X-138
0.37
uM
LJP6
 1
F22
 72
hr
 868 2593 3429 0.7560 0.7368
MDA-MB-231 QL-X-138
0.37
uM
LJP6
 2
F22
 72
hr
 868 2811 3652 0.7697 0.7627
MDA-MB-231 QL-X-138
0.37
uM
LJP6
 3
F22
 72
hr
 868 2581 3587 0.7195 0.7029
MDA-MB-231 QL-X-138
1.11
uM
LJP6
 1
F21
 72
hr
 868 2529 3429 0.7374 0.7150
MDA-MB-231 QL-X-138
1.11
uM
LJP6
 2
F21
 72
hr
 868 2545 3652 0.6969 0.6802
MDA-MB-231 QL-X-138
1.11
uM
LJP6
 3
F21
 72
hr
 868 2377 3587 0.6626 0.6357
MDA-MB-231 QL-X-138
3.33
uM
LJP6
 1
F20
 72
hr
 868 2049 3429 0.5974 0.5423
MDA-MB-231 QL-X-138
3.33
uM
LJP6
 2
F20
 72
hr
 868 1928 3652 0.5279 0.4696
MDA-MB-231 QL-X-138
3.33
uM
LJP6
 3
F20
 72
hr
 868 1865 3587 0.5199 0.4529
MDA-MB-231 QL-X-138
10
uM
LJP6
 1
F19
 72
hr
 868 847 3429 0.2470 -0.0123
MDA-MB-231 QL-X-138
10
uM
LJP6
 2
F19
 72
hr
 868 836 3652 0.2289 -0.0180
MDA-MB-231 QL-X-138
10
uM
LJP6
 3
F19
 72
hr
 868 865 3587 0.2411 -0.0018
MDA-MB-231 QL-XII-47
0.04
uM
LJP6
 1
O24
 72
hr
 868 2329 3429 0.6791 0.6452
MDA-MB-231 QL-XII-47
0.04
uM
LJP6
 2
O24
 72
hr
 868 2516 3652 0.6889 0.6709
MDA-MB-231 QL-XII-47
0.04
uM
LJP6
 3
O24
 72
hr
 868 2333 3587 0.6504 0.6209
MDA-MB-231 QL-XII-47
0.12
uM
LJP6
 1
O23
 72
hr
 868 2102 3429 0.6129 0.5623
MDA-MB-231 QL-XII-47
0.12
uM
LJP6
 2
O23
 72
hr
 868 2147 3652 0.5879 0.5479
MDA-MB-231 QL-XII-47
0.12
uM
LJP6
 3
O23
 72
hr
 868 1942 3587 0.5414 0.4819
MDA-MB-231 QL-XII-47
0.37
uM
LJP6
 1
O22
 72
hr
 868 1283 3429 0.3741 0.2178
MDA-MB-231 QL-XII-47
0.37
uM
LJP6
 2
O22
 72
hr
 868 1453 3652 0.3979 0.2821
MDA-MB-231 QL-XII-47
0.37
uM
LJP6
 3
O22
 72
hr
 868 1592 3587 0.4438 0.3448
MDA-MB-231 QL-XII-47
1.11
uM
LJP6
 1
O21
 72
hr
 868 999 3429 0.2913 0.0734
MDA-MB-231 QL-XII-47
1.11
uM
LJP6
 2
O21
 72
hr
 868 1085 3652 0.2971 0.1136
MDA-MB-231 QL-XII-47
1.11
uM
LJP6
 3
O21
 72
hr
 868 970 3587 0.2704 0.0557