LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Geldanamycin
0.12
uM
LJP5
 2
O05
 72
hr
 868 1053 3505 0.3004 0.1006
MDA-MB-231 Geldanamycin
0.12
uM
LJP5
 3
O05
 72
hr
 868 1127 3440 0.3276 0.1404
MDA-MB-231 Geldanamycin
0.37
uM
LJP6
 1
O04
 72
hr
 868 1308 3429 0.3814 0.2298
MDA-MB-231 Geldanamycin
0.37
uM
LJP6
 2
O04
 72
hr
 868 1367 3652 0.3743 0.2449
MDA-MB-231 Geldanamycin
0.37
uM
LJP6
 3
O04
 72
hr
 868 1294 3587 0.3607 0.2153
MDA-MB-231 Geldanamycin
0.37
uM
LJP5
 1
O04
 72
hr
 868 1236 3286 0.3761 0.2020
MDA-MB-231 Geldanamycin
0.37
uM
LJP5
 2
O04
 72
hr
 868 1248 3505 0.3560 0.1975
MDA-MB-231 Geldanamycin
0.37
uM
LJP5
 3
O04
 72
hr
 868 1237 3440 0.3596 0.1951
MDA-MB-231 Geldanamycin
1.11
uM
LJP6
 1
O03
 72
hr
 868 1110 3429 0.3236 0.1320
MDA-MB-231 Geldanamycin
1.11
uM
LJP6
 2
O03
 72
hr
 868 1271 3652 0.3480 0.2019
MDA-MB-231 Geldanamycin
1.11
uM
LJP6
 3
O03
 72
hr
 868 1135 3587 0.3164 0.1399
MDA-MB-231 Geldanamycin
1.11
uM
LJP5
 1
O03
 72
hr
 868 1116 3286 0.3396 0.1397
MDA-MB-231 Geldanamycin
1.11
uM
LJP5
 2
O03
 72
hr
 868 1012 3505 0.2887 0.0791
MDA-MB-231 Geldanamycin
1.11
uM
LJP5
 3
O03
 72
hr
 868 1058 3440 0.3075 0.1047
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 1
O02
 72
hr
 868 919 3429 0.2680 0.0292
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 2
O02
 72
hr
 868 854 3652 0.2338 -0.0079
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 3
O02
 72
hr
 868 1120 3587 0.3122 0.1325
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 1
O02
 72
hr
 868 926 3286 0.2818 0.0342
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 2
O02
 72
hr
 868 762 3505 0.2174 -0.0627
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 3
O02
 72
hr
 868 890 3440 0.2587 0.0126
MDA-MB-231 Geldanamycin
10
uM
LJP6
 1
O01
 72
hr
 868 582 3429 0.1697 -0.1827
MDA-MB-231 Geldanamycin
10
uM
LJP6
 2
O01
 72
hr
 868 532 3652 0.1457 -0.2104
MDA-MB-231 Geldanamycin
10
uM
LJP6
 3
O01
 72
hr
 868 551 3587 0.1536 -0.1992
MDA-MB-231 Geldanamycin
10
uM
LJP5
 1
O01
 72
hr
 868 638 3286 0.1941 -0.1482
MDA-MB-231 Geldanamycin
10
uM
LJP5
 2
O01
 72
hr
 868 529 3505 0.1509 -0.2181