LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Geldanamycin
10
uM
LJP5
 3
O01
 72
hr
 868 643 3440 0.1869 -0.1402
MDA-MB-231 YM 201636
0.04
uM
LJP5
 1
N12
 72
hr
 868 3401 3286 1.0349 1.0361
MDA-MB-231 YM 201636
0.04
uM
LJP5
 2
N12
 72
hr
 868 4088 3505 1.1662 1.1587
MDA-MB-231 YM 201636
0.04
uM
LJP5
 3
N12
 72
hr
 868 3330 3440 0.9679 0.9675
MDA-MB-231 YM 201636
0.12
uM
LJP5
 1
N11
 72
hr
 868 2973 3286 0.9047 0.8983
MDA-MB-231 YM 201636
0.12
uM
LJP5
 2
N11
 72
hr
 868 3809 3505 1.0866 1.0842
MDA-MB-231 YM 201636
0.12
uM
LJP5
 3
N11
 72
hr
 868 3185 3440 0.9258 0.9239
MDA-MB-231 YM 201636
0.37
uM
LJP5
 1
N10
 72
hr
 868 2924 3286 0.8898 0.8820
MDA-MB-231 YM 201636
0.37
uM
LJP5
 2
N10
 72
hr
 868 3466 3505 0.9888 0.9888
MDA-MB-231 YM 201636
0.37
uM
LJP5
 3
N10
 72
hr
 868 3038 3440 0.8831 0.8786
MDA-MB-231 YM 201636
1.11
uM
LJP5
 1
N09
 72
hr
 868 2699 3286 0.8213 0.8051
MDA-MB-231 YM 201636
1.11
uM
LJP5
 2
N09
 72
hr
 868 3029 3505 0.8641 0.8601
MDA-MB-231 YM 201636
1.11
uM
LJP5
 3
N09
 72
hr
 868 2797 3440 0.8130 0.8021
MDA-MB-231 YM 201636
3.33
uM
LJP5
 1
N08
 72
hr
 868 2682 3286 0.8161 0.7992
MDA-MB-231 YM 201636
3.33
uM
LJP5
 2
N08
 72
hr
 868 2701 3505 0.7705 0.7571
MDA-MB-231 YM 201636
3.33
uM
LJP5
 3
N08
 72
hr
 868 2590 3440 0.7528 0.7337
MDA-MB-231 YM 201636
10
uM
LJP5
 1
N07
 72
hr
 868 1640 3286 0.4990 0.3927
MDA-MB-231 YM 201636
10
uM
LJP5
 2
N07
 72
hr
 868 1679 3505 0.4790 0.3876
MDA-MB-231 YM 201636
10
uM
LJP5
 3
N07
 72
hr
 868 1474 3440 0.4285 0.3054
MDA-MB-231 TWS119
0.04
uM
LJP5
 1
M06
 72
hr
 868 3201 3286 0.9741 0.9728
MDA-MB-231 TWS119
0.04
uM
LJP5
 2
M06
 72
hr
 868 3653 3505 1.0421 1.0414
MDA-MB-231 TWS119
0.04
uM
LJP5
 3
M06
 72
hr
 868 3259 3440 0.9473 0.9462
MDA-MB-231 TWS119
0.12
uM
LJP5
 1
M05
 72
hr
 868 3348 3286 1.0188 1.0195
MDA-MB-231 TWS119
0.12
uM
LJP5
 2
M05
 72
hr
 868 3777 3505 1.0775 1.0755
MDA-MB-231 TWS119
0.12
uM
LJP5
 3
M05
 72
hr
 868 3447 3440 1.0020 1.0020