LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 SNS-032
10
uM
LJP6
 1
H13
 72
hr
 868 687 3429 0.2003 -0.1114
MDA-MB-231 SNS-032
10
uM
LJP6
 2
H13
 72
hr
 868 866 3652 0.2371 -0.0012
MDA-MB-231 SNS-032
10
uM
LJP6
 3
H13
 72
hr
 868 794 3587 0.2213 -0.0427
MDA-MB-231 Afatinib
0.04
uM
LJP6
 1
G24
 72
hr
 868 2415 3429 0.7041 0.6756
MDA-MB-231 Afatinib
0.04
uM
LJP6
 2
G24
 72
hr
 868 2747 3652 0.7522 0.7433
MDA-MB-231 Afatinib
0.04
uM
LJP6
 3
G24
 72
hr
 868 2487 3587 0.6933 0.6723
MDA-MB-231 Afatinib
0.12
uM
LJP6
 1
G23
 72
hr
 868 2821 3429 0.8225 0.8122
MDA-MB-231 Afatinib
0.12
uM
LJP6
 2
G23
 72
hr
 868 2975 3652 0.8146 0.8116
MDA-MB-231 Afatinib
0.12
uM
LJP6
 3
G23
 72
hr
 868 3049 3587 0.8500 0.8473
MDA-MB-231 Afatinib
0.37
uM
LJP6
 1
G22
 72
hr
 868 2813 3429 0.8202 0.8097
MDA-MB-231 Afatinib
0.37
uM
LJP6
 2
G22
 72
hr
 868 3027 3652 0.8289 0.8268
MDA-MB-231 Afatinib
0.37
uM
LJP6
 3
G22
 72
hr
 868 2482 3587 0.6919 0.6706
MDA-MB-231 Afatinib
1.11
uM
LJP6
 1
G21
 72
hr
 868 2455 3429 0.7158 0.6895
MDA-MB-231 Afatinib
1.11
uM
LJP6
 2
G21
 72
hr
 868 2627 3652 0.7193 0.7061
MDA-MB-231 Afatinib
1.11
uM
LJP6
 3
G21
 72
hr
 868 2797 3587 0.7797 0.7711
MDA-MB-231 Afatinib
3.33
uM
LJP6
 1
G20
 72
hr
 868 2252 3429 0.6566 0.6176
MDA-MB-231 Afatinib
3.33
uM
LJP6
 2
G20
 72
hr
 868 2069 3652 0.5665 0.5205
MDA-MB-231 Afatinib
3.33
uM
LJP6
 3
G20
 72
hr
 868 2226 3587 0.6205 0.5841
MDA-MB-231 Afatinib
10
uM
LJP6
 1
G19
 72
hr
 868 606 3429 0.1767 -0.1659
MDA-MB-231 Afatinib
10
uM
LJP6
 2
G19
 72
hr
 868 822 3652 0.2251 -0.0260
MDA-MB-231 Afatinib
10
uM
LJP6
 3
G19
 72
hr
 868 769 3587 0.2144 -0.0575
MDA-MB-231 GSK1904529A
0.04
uM
LJP6
 1
H24
 72
hr
 868 2409 3429 0.7024 0.6735
MDA-MB-231 GSK1904529A
0.04
uM
LJP6
 2
H24
 72
hr
 868 2842 3652 0.7782 0.7721
MDA-MB-231 GSK1904529A
0.04
uM
LJP6
 3
H24
 72
hr
 868 2514 3587 0.7008 0.6811
MDA-MB-231 GSK1904529A
0.12
uM
LJP6
 1
H23
 72
hr
 868 2672 3429 0.7791 0.7633