LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 AZD 5438
3.33
uM
LJP6
 2
J02
 72
hr
 868 831 3652 0.2276 -0.0209
MDA-MB-231 AZD 5438
3.33
uM
LJP6
 3
J02
 72
hr
 868 720 3587 0.2007 -0.0873
MDA-MB-231 AZD 5438
10
uM
LJP6
 1
J01
 72
hr
 868 639 3429 0.1863 -0.1432
MDA-MB-231 AZD 5438
10
uM
LJP6
 2
J01
 72
hr
 868 659 3652 0.1805 -0.1245
MDA-MB-231 AZD 5438
10
uM
LJP6
 3
J01
 72
hr
 868 668 3587 0.1862 -0.1202
MDA-MB-231 Pelitinib
0.04
uM
LJP5
 1
I18
 72
hr
 868 3879 3286 1.1804 1.1804
MDA-MB-231 Pelitinib
0.04
uM
LJP5
 2
I18
 72
hr
 868 3816 3505 1.0886 1.0861
MDA-MB-231 Pelitinib
0.04
uM
LJP5
 3
I18
 72
hr
 868 3528 3440 1.0255 1.0255
MDA-MB-231 Pelitinib
0.12
uM
LJP5
 1
I17
 72
hr
 868 3436 3286 1.0456 1.0469
MDA-MB-231 Pelitinib
0.12
uM
LJP5
 2
I17
 72
hr
 868 3864 3505 1.1023 1.0991
MDA-MB-231 Pelitinib
0.12
uM
LJP5
 3
I17
 72
hr
 868 3687 3440 1.0717 1.0710
MDA-MB-231 Pelitinib
0.37
uM
LJP5
 1
I16
 72
hr
 868 2699 3286 0.8213 0.8051
MDA-MB-231 Pelitinib
0.37
uM
LJP5
 2
I16
 72
hr
 868 3014 3505 0.8598 0.8555
MDA-MB-231 Pelitinib
0.37
uM
LJP5
 3
I16
 72
hr
 868 2890 3440 0.8401 0.8320
MDA-MB-231 Pelitinib
1.11
uM
LJP5
 1
I15
 72
hr
 868 2578 3286 0.7845 0.7625
MDA-MB-231 Pelitinib
1.11
uM
LJP5
 2
I15
 72
hr
 868 2957 3505 0.8436 0.8380
MDA-MB-231 Pelitinib
1.11
uM
LJP5
 3
I15
 72
hr
 868 2636 3440 0.7662 0.7491
MDA-MB-231 Pelitinib
3.33
uM
LJP5
 1
I14
 72
hr
 868 1535 3286 0.4671 0.3455
MDA-MB-231 Pelitinib
3.33
uM
LJP5
 2
I14
 72
hr
 868 1655 3505 0.4721 0.3777
MDA-MB-231 Pelitinib
3.33
uM
LJP5
 3
I14
 72
hr
 868 1416 3440 0.4116 0.2793
MDA-MB-231 Pelitinib
10
uM
LJP5
 1
I13
 72
hr
 868 691 3286 0.2103 -0.1120
MDA-MB-231 Pelitinib
10
uM
LJP5
 2
I13
 72
hr
 868 744 3505 0.2122 -0.0738
MDA-MB-231 Pelitinib
10
uM
LJP5
 3
I13
 72
hr
 868 704 3440 0.2046 -0.1001
MDA-MB-231 Luminespib
0.04
uM
LJP5
 1
H18
 72
hr
 868 1065 3286 0.3241 0.1123
MDA-MB-231 Luminespib
0.04
uM
LJP5
 2
H18
 72
hr
 868 984 3505 0.2807 0.0642