LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 AZD-6482
1.11
uM
LJP5
 2
I03
 72
hr
 868 2325 3505 0.6633 0.6311
MDA-MB-231 AZD-6482
1.11
uM
LJP5
 3
I03
 72
hr
 868 2529 3440 0.7351 0.7130
MDA-MB-231 AZD-6482
3.33
uM
LJP5
 1
I02
 72
hr
 868 1697 3286 0.5164 0.4177
MDA-MB-231 AZD-6482
3.33
uM
LJP5
 2
I02
 72
hr
 868 1995 3505 0.5691 0.5117
MDA-MB-231 AZD-6482
3.33
uM
LJP5
 3
I02
 72
hr
 868 2289 3440 0.6654 0.6291
MDA-MB-231 AZD-6482
10
uM
LJP5
 1
I01
 72
hr
 868 1109 3286 0.3375 0.1360
MDA-MB-231 AZD-6482
10
uM
LJP5
 2
I01
 72
hr
 868 1233 3505 0.3517 0.1904
MDA-MB-231 AZD-6482
10
uM
LJP5
 3
I01
 72
hr
 868 1439 3440 0.4183 0.2897
MDA-MB-231 NU7441
0.04
uM
LJP5
 1
C12
 72
hr
 868 3273 3286 0.9960 0.9958
MDA-MB-231 NU7441
0.04
uM
LJP5
 2
C12
 72
hr
 868 3754 3505 1.0709 1.0692
MDA-MB-231 NU7441
0.04
uM
LJP5
 3
C12
 72
hr
 868 3843 3440 1.1171 1.1146
MDA-MB-231 NU7441
0.12
uM
LJP5
 1
C11
 72
hr
 868 3336 3286 1.0151 1.0157
MDA-MB-231 NU7441
0.12
uM
LJP5
 2
C11
 72
hr
 868 2964 3505 0.8456 0.8401
MDA-MB-231 NU7441
0.12
uM
LJP5
 3
C11
 72
hr
 868 3528 3440 1.0255 1.0255
MDA-MB-231 NU7441
0.37
uM
LJP5
 1
C10
 72
hr
 868 2776 3286 0.8447 0.8318
MDA-MB-231 NU7441
0.37
uM
LJP5
 2
C10
 72
hr
 868 2539 3505 0.7243 0.7040
MDA-MB-231 NU7441
0.37
uM
LJP5
 3
C10
 72
hr
 868 3086 3440 0.8970 0.8935
MDA-MB-231 NU7441
1.11
uM
LJP5
 1
C09
 72
hr
 868 2661 3286 0.8097 0.7919
MDA-MB-231 NU7441
1.11
uM
LJP5
 2
C09
 72
hr
 868 2568 3505 0.7326 0.7136
MDA-MB-231 NU7441
1.11
uM
LJP5
 3
C09
 72
hr
 868 2699 3440 0.7845 0.7700
MDA-MB-231 NU7441
3.33
uM
LJP5
 1
C08
 72
hr
 868 2124 3286 0.6463 0.5934
MDA-MB-231 NU7441
3.33
uM
LJP5
 2
C08
 72
hr
 868 2017 3505 0.5754 0.5199
MDA-MB-231 NU7441
3.33
uM
LJP5
 3
C08
 72
hr
 868 1795 3440 0.5218 0.4415
MDA-MB-231 NU7441
10
uM
LJP5
 1
C07
 72
hr
 868 1152 3286 0.3506 0.1587
MDA-MB-231 NU7441
10
uM
LJP5
 2
C07
 72
hr
 868 1184 3505 0.3378 0.1666