LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 MK2206
0.12
uM
LJP6
 1
F05
 72
hr
 868 3095 3429 0.9024 0.8990
MDA-MB-231 MK2206
0.12
uM
LJP6
 2
F05
 72
hr
 868 2890 3652 0.7914 0.7865
MDA-MB-231 MK2206
0.12
uM
LJP6
 3
F05
 72
hr
 868 3291 3587 0.9174 0.9175
MDA-MB-231 MK2206
0.37
uM
LJP6
 1
F04
 72
hr
 868 2806 3429 0.8181 0.8074
MDA-MB-231 MK2206
0.37
uM
LJP6
 2
F04
 72
hr
 868 2720 3652 0.7448 0.7350
MDA-MB-231 MK2206
0.37
uM
LJP6
 3
F04
 72
hr
 868 2761 3587 0.7697 0.7599
MDA-MB-231 MK2206
1.11
uM
LJP6
 1
F03
 72
hr
 868 2625 3429 0.7654 0.7476
MDA-MB-231 MK2206
1.11
uM
LJP6
 2
F03
 72
hr
 868 2772 3652 0.7590 0.7509
MDA-MB-231 MK2206
1.11
uM
LJP6
 3
F03
 72
hr
 868 2633 3587 0.7340 0.7195
MDA-MB-231 MK2206
3.33
uM
LJP6
 1
F02
 72
hr
 868 2377 3429 0.6931 0.6622
MDA-MB-231 MK2206
3.33
uM
LJP6
 2
F02
 72
hr
 868 2801 3652 0.7670 0.7597
MDA-MB-231 MK2206
3.33
uM
LJP6
 3
F02
 72
hr
 868 2578 3587 0.7187 0.7019
MDA-MB-231 MK2206
10
uM
LJP6
 1
F01
 72
hr
 868 1122 3429 0.3271 0.1382
MDA-MB-231 MK2206
10
uM
LJP6
 2
F01
 72
hr
 868 1014 3652 0.2777 0.0778
MDA-MB-231 MK2206
10
uM
LJP6
 3
F01
 72
hr
 868 1282 3587 0.3574 0.2098
MDA-MB-231 AZD-6482
0.04
uM
LJP5
 1
I06
 72
hr
 868 2923 3286 0.8895 0.8817
MDA-MB-231 AZD-6482
0.04
uM
LJP5
 2
I06
 72
hr
 868 3511 3505 1.0016 1.0016
MDA-MB-231 AZD-6482
0.04
uM
LJP5
 3
I06
 72
hr
 868 3100 3440 0.9011 0.8978
MDA-MB-231 AZD-6482
0.12
uM
LJP5
 1
I05
 72
hr
 868 3043 3286 0.9260 0.9215
MDA-MB-231 AZD-6482
0.12
uM
LJP5
 2
I05
 72
hr
 868 3053 3505 0.8709 0.8674
MDA-MB-231 AZD-6482
0.12
uM
LJP5
 3
I05
 72
hr
 868 3099 3440 0.9008 0.8975
MDA-MB-231 AZD-6482
0.37
uM
LJP5
 1
I04
 72
hr
 868 2986 3286 0.9086 0.9027
MDA-MB-231 AZD-6482
0.37
uM
LJP5
 2
I04
 72
hr
 868 3179 3505 0.9069 0.9052
MDA-MB-231 AZD-6482
0.37
uM
LJP5
 3
I04
 72
hr
 868 2916 3440 0.8476 0.8403
MDA-MB-231 AZD-6482
1.11
uM
LJP5
 1
I03
 72
hr
 868 2213 3286 0.6734 0.6279