LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Sigma A6730
0.12
uM
LJP5
 3
B23
 72
hr
 868 2839 3440 0.8252 0.8157
MDA-MB-231 Sigma A6730
0.37
uM
LJP5
 1
B22
 72
hr
 868 2938 3286 0.8940 0.8867
MDA-MB-231 Sigma A6730
0.37
uM
LJP5
 2
B22
 72
hr
 868 3031 3505 0.8647 0.8607
MDA-MB-231 Sigma A6730
0.37
uM
LJP5
 3
B22
 72
hr
 868 2945 3440 0.8560 0.8495
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 1
B21
 72
hr
 868 2485 3286 0.7562 0.7291
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 2
B21
 72
hr
 868 2650 3505 0.7560 0.7406
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 3
B21
 72
hr
 868 2700 3440 0.7848 0.7704
MDA-MB-231 Sigma A6730
3.33
uM
LJP5
 1
B20
 72
hr
 868 2882 3286 0.8770 0.8679
MDA-MB-231 Sigma A6730
3.33
uM
LJP5
 2
B20
 72
hr
 868 2993 3505 0.8538 0.8490
MDA-MB-231 Sigma A6730
3.33
uM
LJP5
 3
B20
 72
hr
 868 3005 3440 0.8735 0.8683
MDA-MB-231 Sigma A6730
10
uM
LJP5
 1
B19
 72
hr
 868 2040 3286 0.6208 0.5603
MDA-MB-231 Sigma A6730
10
uM
LJP5
 2
B19
 72
hr
 868 1777 3505 0.5069 0.4273
MDA-MB-231 Sigma A6730
10
uM
LJP5
 3
B19
 72
hr
 868 1921 3440 0.5584 0.4916
MDA-MB-231 WH-4-025
0.04
uM
LJP5
 1
O12
 72
hr
 868 2739 3286 0.8335 0.8190
MDA-MB-231 WH-4-025
0.04
uM
LJP5
 2
O12
 72
hr
 868 2946 3505 0.8404 0.8346
MDA-MB-231 WH-4-025
0.04
uM
LJP5
 3
O12
 72
hr
 868 2781 3440 0.8084 0.7969
MDA-MB-231 WH-4-025
0.12
uM
LJP5
 1
O11
 72
hr
 868 1511 3286 0.4598 0.3345
MDA-MB-231 WH-4-025
0.12
uM
LJP5
 2
O11
 72
hr
 868 1774 3505 0.5061 0.4261
MDA-MB-231 WH-4-025
0.12
uM
LJP5
 3
O11
 72
hr
 868 1604 3440 0.4662 0.3621
MDA-MB-231 WH-4-025
0.37
uM
LJP5
 1
O10
 72
hr
 868 1246 3286 0.3792 0.2070
MDA-MB-231 WH-4-025
0.37
uM
LJP5
 2
O10
 72
hr
 868 1403 3505 0.4002 0.2692
MDA-MB-231 WH-4-025
0.37
uM
LJP5
 3
O10
 72
hr
 868 1386 3440 0.4029 0.2656
MDA-MB-231 WH-4-025
1.11
uM
LJP5
 1
O09
 72
hr
 868 657 3286 0.1999 -0.1351
MDA-MB-231 WH-4-025
1.11
uM
LJP5
 2
O09
 72
hr
 868 804 3505 0.2294 -0.0374
MDA-MB-231 WH-4-025
1.11
uM
LJP5
 3
O09
 72
hr
 868 851 3440 0.2474 -0.0100