LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 KIN001-043
10
uM
LJP6
 2
C07
 72
hr
 868 1990 3652 0.5449 0.4922
MDA-MB-231 KIN001-043
10
uM
LJP6
 3
C07
 72
hr
 868 1890 3587 0.5269 0.4624
MDA-MB-231 Saracatinib
0.04
uM
LJP6
 1
D12
 72
hr
 868 3495 3429 1.0190 1.0191
MDA-MB-231 Saracatinib
0.04
uM
LJP6
 2
D12
 72
hr
 868 3283 3652 0.8990 0.8998
MDA-MB-231 Saracatinib
0.04
uM
LJP6
 3
D12
 72
hr
 868 3237 3587 0.9024 0.9021
MDA-MB-231 Saracatinib
0.12
uM
LJP6
 1
D11
 72
hr
 868 3254 3429 0.9488 0.9476
MDA-MB-231 Saracatinib
0.12
uM
LJP6
 2
D11
 72
hr
 868 2696 3652 0.7382 0.7276
MDA-MB-231 Saracatinib
0.12
uM
LJP6
 3
D11
 72
hr
 868 2594 3587 0.7231 0.7071
MDA-MB-231 Saracatinib
0.37
uM
LJP6
 1
D10
 72
hr
 868 2563 3429 0.7473 0.7266
MDA-MB-231 Saracatinib
0.37
uM
LJP6
 2
D10
 72
hr
 868 2255 3652 0.6175 0.5849
MDA-MB-231 Saracatinib
0.37
uM
LJP6
 3
D10
 72
hr
 868 2336 3587 0.6512 0.6219
MDA-MB-231 Saracatinib
1.11
uM
LJP6
 1
D09
 72
hr
 868 2217 3429 0.6464 0.6048
MDA-MB-231 Saracatinib
1.11
uM
LJP6
 2
D09
 72
hr
 868 1995 3652 0.5463 0.4940
MDA-MB-231 Saracatinib
1.11
uM
LJP6
 3
D09
 72
hr
 868 2131 3587 0.5940 0.5507
MDA-MB-231 Saracatinib
3.33
uM
LJP6
 1
D08
 72
hr
 868 2455 3429 0.7158 0.6895
MDA-MB-231 Saracatinib
3.33
uM
LJP6
 2
D08
 72
hr
 868 2111 3652 0.5780 0.5353
MDA-MB-231 Saracatinib
3.33
uM
LJP6
 3
D08
 72
hr
 868 2149 3587 0.5991 0.5571
MDA-MB-231 Saracatinib
10
uM
LJP6
 1
D07
 72
hr
 868 1976 3429 0.5761 0.5143
MDA-MB-231 Saracatinib
10
uM
LJP6
 2
D07
 72
hr
 868 1893 3652 0.5184 0.4566
MDA-MB-231 Saracatinib
10
uM
LJP6
 3
D07
 72
hr
 868 1818 3587 0.5068 0.4349
MDA-MB-231 Sigma A6730
0.04
uM
LJP5
 1
B24
 72
hr
 868 2439 3286 0.7422 0.7124
MDA-MB-231 Sigma A6730
0.04
uM
LJP5
 2
B24
 72
hr
 868 2794 3505 0.7971 0.7869
MDA-MB-231 Sigma A6730
0.04
uM
LJP5
 3
B24
 72
hr
 868 2982 3440 0.8668 0.8611
MDA-MB-231 Sigma A6730
0.12
uM
LJP5
 1
B23
 72
hr
 868 2617 3286 0.7963 0.7764
MDA-MB-231 Sigma A6730
0.12
uM
LJP5
 2
B23
 72
hr
 868 2785 3505 0.7945 0.7841