LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 HG-6-64-01
0.04
uM
LJP6
 1
M06
 72
hr
 868 3606 3429 1.0514 1.0512
MDA-MB-231 HG-6-64-01
0.04
uM
LJP6
 2
M06
 72
hr
 868 3823 3652 1.0468 1.0446
MDA-MB-231 HG-6-64-01
0.04
uM
LJP6
 3
M06
 72
hr
 868 3838 3587 1.0699 1.0671
MDA-MB-231 HG-6-64-01
0.12
uM
LJP6
 1
M05
 72
hr
 868 3669 3429 1.0697 1.0692
MDA-MB-231 HG-6-64-01
0.12
uM
LJP6
 2
M05
 72
hr
 868 3661 3652 1.0025 1.0024
MDA-MB-231 HG-6-64-01
0.12
uM
LJP6
 3
M05
 72
hr
 868 3579 3587 0.9977 0.9977
MDA-MB-231 HG-6-64-01
0.37
uM
LJP6
 1
M04
 72
hr
 868 2737 3429 0.7980 0.7848
MDA-MB-231 HG-6-64-01
0.37
uM
LJP6
 2
M04
 72
hr
 868 2736 3652 0.7492 0.7399
MDA-MB-231 HG-6-64-01
0.37
uM
LJP6
 3
M04
 72
hr
 868 2792 3587 0.7783 0.7695
MDA-MB-231 HG-6-64-01
1.11
uM
LJP6
 1
M03
 72
hr
 868 1684 3429 0.4910 0.3969
MDA-MB-231 HG-6-64-01
1.11
uM
LJP6
 2
M03
 72
hr
 868 1720 3652 0.4710 0.3908
MDA-MB-231 HG-6-64-01
1.11
uM
LJP6
 3
M03
 72
hr
 868 1644 3587 0.4583 0.3661
MDA-MB-231 HG-6-64-01
3.33
uM
LJP6
 1
M02
 72
hr
 868 870 3429 0.2537 0.0011
MDA-MB-231 HG-6-64-01
3.33
uM
LJP6
 2
M02
 72
hr
 868 1037 3652 0.2840 0.0895
MDA-MB-231 HG-6-64-01
3.33
uM
LJP6
 3
M02
 72
hr
 868 1228 3587 0.3423 0.1846
MDA-MB-231 HG-6-64-01
10
uM
LJP6
 1
M01
 72
hr
 868 509 3429 0.1484 -0.2361
MDA-MB-231 HG-6-64-01
10
uM
LJP6
 2
M01
 72
hr
 868 452 3652 0.1238 -0.2701
MDA-MB-231 HG-6-64-01
10
uM
LJP6
 3
M01
 72
hr
 868 618 3587 0.1723 -0.1530
MDA-MB-231 Neratinib
0.04
uM
LJP5
 1
A18
 72
hr
 868 2675 3286 0.8140 0.7968
MDA-MB-231 Neratinib
0.04
uM
LJP5
 2
A18
 72
hr
 868 2403 3505 0.6855 0.6580
MDA-MB-231 Neratinib
0.04
uM
LJP5
 3
A18
 72
hr
 868 2886 3440 0.8389 0.8307
MDA-MB-231 Neratinib
0.12
uM
LJP5
 1
A17
 72
hr
 868 2358 3286 0.7175 0.6825
MDA-MB-231 Neratinib
0.12
uM
LJP5
 2
A17
 72
hr
 868 2438 3505 0.6955 0.6700
MDA-MB-231 Neratinib
0.12
uM
LJP5
 3
A17
 72
hr
 868 2568 3440 0.7465 0.7262
MDA-MB-231 Neratinib
0.37
uM
LJP5
 1
A16
 72
hr
 868 2225 3286 0.6771 0.6324