LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 WH-4-025
3.33
uM
LJP5
 1
O08
 72
hr
 868 793 3286 0.2413 -0.0460
MDA-MB-231 WH-4-025
3.33
uM
LJP5
 2
O08
 72
hr
 868 815 3505 0.2325 -0.0309
MDA-MB-231 WH-4-025
3.33
uM
LJP5
 3
O08
 72
hr
 868 826 3440 0.2401 -0.0247
MDA-MB-231 WH-4-025
10
uM
LJP5
 1
O07
 72
hr
 868 724 3286 0.2203 -0.0902
MDA-MB-231 WH-4-025
10
uM
LJP5
 2
O07
 72
hr
 868 720 3505 0.2054 -0.0887
MDA-MB-231 WH-4-025
10
uM
LJP5
 3
O07
 72
hr
 868 825 3440 0.2398 -0.0253
MDA-MB-231 R406
0.04
uM
LJP6
 1
C18
 72
hr
 868 3676 3429 1.0718 1.0712
MDA-MB-231 R406
0.04
uM
LJP6
 2
C18
 72
hr
 868 3196 3652 0.8751 0.8754
MDA-MB-231 R406
0.04
uM
LJP6
 3
C18
 72
hr
 868 3413 3587 0.9514 0.9519
MDA-MB-231 R406
0.12
uM
LJP6
 1
C17
 72
hr
 868 3279 3429 0.9560 0.9552
MDA-MB-231 R406
0.12
uM
LJP6
 2
C17
 72
hr
 868 3141 3652 0.8601 0.8597
MDA-MB-231 R406
0.12
uM
LJP6
 3
C17
 72
hr
 868 3186 3587 0.8881 0.8874
MDA-MB-231 R406
0.37
uM
LJP6
 1
C16
 72
hr
 868 3287 3429 0.9584 0.9576
MDA-MB-231 R406
0.37
uM
LJP6
 2
C16
 72
hr
 868 2724 3652 0.7459 0.7362
MDA-MB-231 R406
0.37
uM
LJP6
 3
C16
 72
hr
 868 3080 3587 0.8586 0.8564
MDA-MB-231 R406
1.11
uM
LJP6
 1
C15
 72
hr
 868 3082 3429 0.8986 0.8950
MDA-MB-231 R406
1.11
uM
LJP6
 2
C15
 72
hr
 868 2739 3652 0.7500 0.7408
MDA-MB-231 R406
1.11
uM
LJP6
 3
C15
 72
hr
 868 2562 3587 0.7142 0.6967
MDA-MB-231 R406
3.33
uM
LJP6
 1
C14
 72
hr
 868 2515 3429 0.7333 0.7103
MDA-MB-231 R406
3.33
uM
LJP6
 2
C14
 72
hr
 868 2425 3652 0.6640 0.6415
MDA-MB-231 R406
3.33
uM
LJP6
 3
C14
 72
hr
 868 2376 3587 0.6623 0.6354
MDA-MB-231 R406
10
uM
LJP6
 1
C13
 72
hr
 868 1789 3429 0.5216 0.4402
MDA-MB-231 R406
10
uM
LJP6
 2
C13
 72
hr
 868 1532 3652 0.4195 0.3153
MDA-MB-231 R406
10
uM
LJP6
 3
C13
 72
hr
 868 1756 3587 0.4895 0.4108
MDA-MB-231 BI-2536
0.04
uM
LJP6
 1
D18
 72
hr
 868 1160 3429 0.3382 0.1575