LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 JW-7-24-1
3.33
uM
LJP6
 3
B20
 72
hr
 868 1833 3587 0.5110 0.4407
MDA-MB-231 JW-7-24-1
10
uM
LJP6
 1
B19
 72
hr
 868 849 3429 0.2475 -0.0112
MDA-MB-231 JW-7-24-1
10
uM
LJP6
 2
B19
 72
hr
 868 841 3652 0.2303 -0.0152
MDA-MB-231 JW-7-24-1
10
uM
LJP6
 3
B19
 72
hr
 868 940 3587 0.2620 0.0396
MDA-MB-231 Dasatinib
0.04
uM
LJP6
 1
I06
 72
hr
 868 719 3429 0.2096 -0.0907
MDA-MB-231 Dasatinib
0.04
uM
LJP6
 2
I06
 72
hr
 868 771 3652 0.2111 -0.0556
MDA-MB-231 Dasatinib
0.04
uM
LJP6
 3
I06
 72
hr
 868 841 3587 0.2344 -0.0154
MDA-MB-231 Dasatinib
0.04
uM
LJP5
 1
D06
 72
hr
 868 1762 3286 0.5362 0.4457
MDA-MB-231 Dasatinib
0.04
uM
LJP5
 2
D06
 72
hr
 868 1489 3505 0.4248 0.3073
MDA-MB-231 Dasatinib
0.04
uM
LJP5
 3
D06
 72
hr
 868 1694 3440 0.4924 0.4001
MDA-MB-231 Dasatinib
0.12
uM
LJP6
 1
I05
 72
hr
 868 632 3429 0.1843 -0.1480
MDA-MB-231 Dasatinib
0.12
uM
LJP6
 2
I05
 72
hr
 868 639 3652 0.1750 -0.1374
MDA-MB-231 Dasatinib
0.12
uM
LJP6
 3
I05
 72
hr
 868 474 3587 0.1321 -0.2559
MDA-MB-231 Dasatinib
0.12
uM
LJP5
 1
D05
 72
hr
 868 686 3286 0.2088 -0.1154
MDA-MB-231 Dasatinib
0.12
uM
LJP5
 2
D05
 72
hr
 868 811 3505 0.2314 -0.0332
MDA-MB-231 Dasatinib
0.12
uM
LJP5
 3
D05
 72
hr
 868 713 3440 0.2073 -0.0943
MDA-MB-231 Dasatinib
0.37
uM
LJP6
 1
I04
 72
hr
 868 583 3429 0.1700 -0.1820
MDA-MB-231 Dasatinib
0.37
uM
LJP6
 2
I04
 72
hr
 868 568 3652 0.1555 -0.1851
MDA-MB-231 Dasatinib
0.37
uM
LJP6
 3
I04
 72
hr
 868 484 3587 0.1349 -0.2483
MDA-MB-231 Dasatinib
0.37
uM
LJP5
 1
D04
 72
hr
 868 517 3286 0.1573 -0.2365
MDA-MB-231 Dasatinib
0.37
uM
LJP5
 2
D04
 72
hr
 868 521 3505 0.1486 -0.2240
MDA-MB-231 Dasatinib
0.37
uM
LJP5
 3
D04
 72
hr
 868 451 3440 0.1311 -0.2808
MDA-MB-231 Dasatinib
1.11
uM
LJP6
 1
I03
 72
hr
 868 475 3429 0.1385 -0.2623
MDA-MB-231 Dasatinib
1.11
uM
LJP6
 2
I03
 72
hr
 868 477 3652 0.1306 -0.2509
MDA-MB-231 Dasatinib
1.11
uM
LJP6
 3
I03
 72
hr
 868 572 3587 0.1595 -0.1844