LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Dasatinib
1.11
uM
LJP5
 1
D03
 72
hr
 868 513 3286 0.1561 -0.2396
MDA-MB-231 Dasatinib
1.11
uM
LJP5
 2
D03
 72
hr
 868 488 3505 0.1392 -0.2488
MDA-MB-231 Dasatinib
1.11
uM
LJP5
 3
D03
 72
hr
 868 491 3440 0.1427 -0.2494
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 1
I02
 72
hr
 868 407 3429 0.1187 -0.3176
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 2
I02
 72
hr
 868 504 3652 0.1380 -0.2308
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 3
I02
 72
hr
 868 470 3587 0.1310 -0.2590
MDA-MB-231 Dasatinib
3.33
uM
LJP5
 1
D02
 72
hr
 868 488 3286 0.1485 -0.2591
MDA-MB-231 Dasatinib
3.33
uM
LJP5
 2
D02
 72
hr
 868 510 3505 0.1455 -0.2322
MDA-MB-231 Dasatinib
3.33
uM
LJP5
 3
D02
 72
hr
 868 547 3440 0.1590 -0.2075
MDA-MB-231 Dasatinib
10
uM
LJP6
 1
I01
 72
hr
 868 397 3429 0.1158 -0.3261
MDA-MB-231 Dasatinib
10
uM
LJP6
 2
I01
 72
hr
 868 445 3652 0.1219 -0.2756
MDA-MB-231 Dasatinib
10
uM
LJP6
 3
I01
 72
hr
 868 526 3587 0.1466 -0.2171
MDA-MB-231 Dasatinib
10
uM
LJP5
 1
D01
 72
hr
 868 617 3286 0.1878 -0.1629
MDA-MB-231 Dasatinib
10
uM
LJP5
 2
D01
 72
hr
 868 720 3505 0.2054 -0.0887
MDA-MB-231 Dasatinib
10
uM
LJP5
 3
D01
 72
hr
 868 564 3440 0.1639 -0.1952
MDA-MB-231 Tozasertib
0.04
uM
LJP5
 1
B18
 72
hr
 868 1060 3286 0.3226 0.1096
MDA-MB-231 Tozasertib
0.04
uM
LJP5
 2
B18
 72
hr
 868 995 3505 0.2839 0.0701
MDA-MB-231 Tozasertib
0.04
uM
LJP5
 3
B18
 72
hr
 868 1105 3440 0.3212 0.1291
MDA-MB-231 Tozasertib
0.12
uM
LJP5
 1
B17
 72
hr
 868 1016 3286 0.3092 0.0854
MDA-MB-231 Tozasertib
0.12
uM
LJP5
 2
B17
 72
hr
 868 983 3505 0.2804 0.0637
MDA-MB-231 Tozasertib
0.12
uM
LJP5
 3
B17
 72
hr
 868 1192 3440 0.3465 0.1730
MDA-MB-231 Tozasertib
0.37
uM
LJP5
 1
B16
 72
hr
 868 1129 3286 0.3436 0.1466
MDA-MB-231 Tozasertib
0.37
uM
LJP5
 2
B16
 72
hr
 868 1070 3505 0.3052 0.1094
MDA-MB-231 Tozasertib
0.37
uM
LJP5
 3
B16
 72
hr
 868 1123 3440 0.3264 0.1384
MDA-MB-231 Tozasertib
1.11
uM
LJP5
 1
B15
 72
hr
 868 1064 3286 0.3238 0.1118