LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Tozasertib
1.11
uM
LJP5
 2
B15
 72
hr
 868 1011 3505 0.2884 0.0786
MDA-MB-231 Tozasertib
1.11
uM
LJP5
 3
B15
 72
hr
 868 1160 3440 0.3372 0.1571
MDA-MB-231 Tozasertib
3.33
uM
LJP5
 1
B14
 72
hr
 868 1201 3286 0.3655 0.1841
MDA-MB-231 Tozasertib
3.33
uM
LJP5
 2
B14
 72
hr
 868 1089 3505 0.3107 0.1192
MDA-MB-231 Tozasertib
3.33
uM
LJP5
 3
B14
 72
hr
 868 1094 3440 0.3180 0.1235
MDA-MB-231 Tozasertib
10
uM
LJP5
 1
B13
 72
hr
 868 1345 3286 0.4093 0.2561
MDA-MB-231 Tozasertib
10
uM
LJP5
 2
B13
 72
hr
 868 1306 3505 0.3726 0.2249
MDA-MB-231 Tozasertib
10
uM
LJP5
 3
B13
 72
hr
 868 1397 3440 0.4061 0.2706
MDA-MB-231 Imatinib
0.04
uM
LJP6
 1
N18
 72
hr
 868 3749 3429 1.0931 1.0918
MDA-MB-231 Imatinib
0.04
uM
LJP6
 2
N18
 72
hr
 868 3984 3652 1.0909 1.0857
MDA-MB-231 Imatinib
0.04
uM
LJP6
 3
N18
 72
hr
 868 3770 3587 1.0509 1.0491
MDA-MB-231 Imatinib
0.12
uM
LJP6
 1
N17
 72
hr
 868 3640 3429 1.0613 1.0609
MDA-MB-231 Imatinib
0.12
uM
LJP6
 2
N17
 72
hr
 868 3673 3652 1.0058 1.0055
MDA-MB-231 Imatinib
0.12
uM
LJP6
 3
N17
 72
hr
 868 3746 3587 1.0442 1.0428
MDA-MB-231 Imatinib
0.37
uM
LJP6
 1
N16
 72
hr
 868 3676 3429 1.0718 1.0712
MDA-MB-231 Imatinib
0.37
uM
LJP6
 2
N16
 72
hr
 868 3808 3652 1.0427 1.0408
MDA-MB-231 Imatinib
0.37
uM
LJP6
 3
N16
 72
hr
 868 3852 3587 1.0738 1.0708
MDA-MB-231 Imatinib
1.11
uM
LJP6
 1
N15
 72
hr
 868 3473 3429 1.0126 1.0127
MDA-MB-231 Imatinib
1.11
uM
LJP6
 2
N15
 72
hr
 868 3870 3652 1.0597 1.0567
MDA-MB-231 Imatinib
1.11
uM
LJP6
 3
N15
 72
hr
 868 3927 3587 1.0947 1.0904
MDA-MB-231 Imatinib
3.33
uM
LJP6
 1
N14
 72
hr
 868 3559 3429 1.0377 1.0377
MDA-MB-231 Imatinib
3.33
uM
LJP6
 2
N14
 72
hr
 868 3823 3652 1.0468 1.0446
MDA-MB-231 Imatinib
3.33
uM
LJP6
 3
N14
 72
hr
 868 3710 3587 1.0342 1.0331
MDA-MB-231 Imatinib
10
uM
LJP6
 1
N13
 72
hr
 868 3242 3429 0.9453 0.9440
MDA-MB-231 Imatinib
10
uM
LJP6
 2
N13
 72
hr
 868 3278 3652 0.8976 0.8984