LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Imatinib
10
uM
LJP6
 3
N13
 72
hr
 868 3180 3587 0.8865 0.8857
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 1
K18
 72
hr
 868 3350 3429 0.9767 0.9764
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 2
K18
 72
hr
 868 3206 3652 0.8779 0.8782
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 3
K18
 72
hr
 868 3190 3587 0.8893 0.8885
MDA-MB-231 NVP-TAE684
0.12
uM
LJP6
 1
K17
 72
hr
 868 2158 3429 0.6292 0.5831
MDA-MB-231 NVP-TAE684
0.12
uM
LJP6
 2
K17
 72
hr
 868 2464 3652 0.6747 0.6542
MDA-MB-231 NVP-TAE684
0.12
uM
LJP6
 3
K17
 72
hr
 868 2310 3587 0.6439 0.6130
MDA-MB-231 NVP-TAE684
0.37
uM
LJP6
 1
K16
 72
hr
 868 2589 3429 0.7549 0.7355
MDA-MB-231 NVP-TAE684
0.37
uM
LJP6
 2
K16
 72
hr
 868 2661 3652 0.7286 0.7167
MDA-MB-231 NVP-TAE684
0.37
uM
LJP6
 3
K16
 72
hr
 868 2521 3587 0.7028 0.6834
MDA-MB-231 NVP-TAE684
1.11
uM
LJP6
 1
K15
 72
hr
 868 1765 3429 0.5146 0.4304
MDA-MB-231 NVP-TAE684
1.11
uM
LJP6
 2
K15
 72
hr
 868 1847 3652 0.5058 0.4394
MDA-MB-231 NVP-TAE684
1.11
uM
LJP6
 3
K15
 72
hr
 868 1839 3587 0.5126 0.4430
MDA-MB-231 NVP-TAE684
3.33
uM
LJP6
 1
K14
 72
hr
 868 1355 3429 0.3951 0.2518
MDA-MB-231 NVP-TAE684
3.33
uM
LJP6
 2
K14
 72
hr
 868 1517 3652 0.4154 0.3090
MDA-MB-231 NVP-TAE684
3.33
uM
LJP6
 3
K14
 72
hr
 868 1387 3587 0.3866 0.2572
MDA-MB-231 NVP-TAE684
10
uM
LJP6
 1
K13
 72
hr
 868 678 3429 0.1977 -0.1172
MDA-MB-231 NVP-TAE684
10
uM
LJP6
 2
K13
 72
hr
 868 687 3652 0.1881 -0.1068
MDA-MB-231 NVP-TAE684
10
uM
LJP6
 3
K13
 72
hr
 868 730 3587 0.2035 -0.0812
MDA-MB-231 CGP60474
0.04
uM
LJP6
 1
G06
 72
hr
 868 863 3429 0.2516 -0.0030
MDA-MB-231 CGP60474
0.04
uM
LJP6
 2
G06
 72
hr
 868 874 3652 0.2393 0.0033
MDA-MB-231 CGP60474
0.04
uM
LJP6
 3
G06
 72
hr
 868 873 3587 0.2434 0.0027
MDA-MB-231 CGP60474
0.04
uM
LJP5
 1
F06
 72
hr
 868 2448 3286 0.7449 0.7157
MDA-MB-231 CGP60474
0.04
uM
LJP5
 2
F06
 72
hr
 868 2520 3505 0.7189 0.6976
MDA-MB-231 CGP60474
0.04
uM
LJP5
 3
F06
 72
hr
 868 2226 3440 0.6470 0.6064