LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 AZD7762
3.33
uM
LJP6
 1
L02
 72
hr
 868 678 3429 0.1977 -0.1172
MDA-MB-231 AZD7762
3.33
uM
LJP6
 2
L02
 72
hr
 868 753 3652 0.2062 -0.0663
MDA-MB-231 AZD7762
3.33
uM
LJP6
 3
L02
 72
hr
 868 618 3587 0.1723 -0.1530
MDA-MB-231 AZD7762
10
uM
LJP6
 1
L01
 72
hr
 868 673 3429 0.1962 -0.1205
MDA-MB-231 AZD7762
10
uM
LJP6
 2
L01
 72
hr
 868 645 3652 0.1766 -0.1335
MDA-MB-231 AZD7762
10
uM
LJP6
 3
L01
 72
hr
 868 582 3587 0.1622 -0.1775
MDA-MB-231 AZD8055
0.04
uM
LJP6
 1
A12
 72
hr
 868 2119 3429 0.6178 0.5686
MDA-MB-231 AZD8055
0.04
uM
LJP6
 2
A12
 72
hr
 868 1593 3652 0.4362 0.3403
MDA-MB-231 AZD8055
0.04
uM
LJP6
 3
A12
 72
hr
 868 1691 3587 0.4714 0.3850
MDA-MB-231 AZD8055
0.12
uM
LJP6
 1
A11
 72
hr
 868 1692 3429 0.4933 0.4003
MDA-MB-231 AZD8055
0.12
uM
LJP6
 2
A11
 72
hr
 868 1405 3652 0.3847 0.2615
MDA-MB-231 AZD8055
0.12
uM
LJP6
 3
A11
 72
hr
 868 1132 3587 0.3156 0.1385
MDA-MB-231 AZD8055
0.37
uM
LJP6
 1
A10
 72
hr
 868 1627 3429 0.4744 0.3729
MDA-MB-231 AZD8055
0.37
uM
LJP6
 2
A10
 72
hr
 868 1357 3652 0.3716 0.2405
MDA-MB-231 AZD8055
0.37
uM
LJP6
 3
A10
 72
hr
 868 1111 3587 0.3097 0.1281
MDA-MB-231 AZD8055
1.11
uM
LJP6
 1
A09
 72
hr
 868 1361 3429 0.3968 0.2546
MDA-MB-231 AZD8055
1.11
uM
LJP6
 2
A09
 72
hr
 868 1377 3652 0.3771 0.2493
MDA-MB-231 AZD8055
1.11
uM
LJP6
 3
A09
 72
hr
 868 1283 3587 0.3577 0.2103
MDA-MB-231 AZD8055
3.33
uM
LJP6
 1
A08
 72
hr
 868 1323 3429 0.3857 0.2368
MDA-MB-231 AZD8055
3.33
uM
LJP6
 2
A08
 72
hr
 868 1285 3652 0.3519 0.2083
MDA-MB-231 AZD8055
3.33
uM
LJP6
 3
A08
 72
hr
 868 1174 3587 0.3273 0.1589
MDA-MB-231 AZD8055
10
uM
LJP6
 1
A07
 72
hr
 868 1102 3429 0.3213 0.1279
MDA-MB-231 AZD8055
10
uM
LJP6
 2
A07
 72
hr
 868 929 3652 0.2544 0.0332
MDA-MB-231 AZD8055
10
uM
LJP6
 3
A07
 72
hr
 868 910 3587 0.2537 0.0233
MDA-MB-231 Sorafenib
0.04
uM
LJP6
 1
B12
 72
hr
 868 3644 3429 1.0625 1.0621