LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 AT-7519
0.12
uM
LJP6
 3
K05
 72
hr
 868 2139 3587 0.5963 0.5536
MDA-MB-231 AT-7519
0.37
uM
LJP6
 1
K04
 72
hr
 868 1033 3429 0.3012 0.0917
MDA-MB-231 AT-7519
0.37
uM
LJP6
 2
K04
 72
hr
 868 949 3652 0.2599 0.0439
MDA-MB-231 AT-7519
0.37
uM
LJP6
 3
K04
 72
hr
 868 913 3587 0.2545 0.0249
MDA-MB-231 AT-7519
1.11
uM
LJP6
 1
K03
 72
hr
 868 590 3429 0.1720 -0.1770
MDA-MB-231 AT-7519
1.11
uM
LJP6
 2
K03
 72
hr
 868 729 3652 0.1996 -0.0808
MDA-MB-231 AT-7519
1.11
uM
LJP6
 3
K03
 72
hr
 868 849 3587 0.2367 -0.0108
MDA-MB-231 AT-7519
3.33
uM
LJP6
 1
K02
 72
hr
 868 551 3429 0.1607 -0.2050
MDA-MB-231 AT-7519
3.33
uM
LJP6
 2
K02
 72
hr
 868 559 3652 0.1531 -0.1913
MDA-MB-231 AT-7519
3.33
uM
LJP6
 3
K02
 72
hr
 868 656 3587 0.1829 -0.1279
MDA-MB-231 AT-7519
10
uM
LJP6
 1
K01
 72
hr
 868 481 3429 0.1402 -0.2576
MDA-MB-231 AT-7519
10
uM
LJP6
 2
K01
 72
hr
 868 523 3652 0.1432 -0.2169
MDA-MB-231 AT-7519
10
uM
LJP6
 3
K01
 72
hr
 868 655 3587 0.1826 -0.1286
MDA-MB-231 AZD7762
0.04
uM
LJP6
 1
L06
 72
hr
 868 1815 3429 0.5292 0.4507
MDA-MB-231 AZD7762
0.04
uM
LJP6
 2
L06
 72
hr
 868 2177 3652 0.5961 0.5582
MDA-MB-231 AZD7762
0.04
uM
LJP6
 3
L06
 72
hr
 868 2185 3587 0.6091 0.5698
MDA-MB-231 AZD7762
0.12
uM
LJP6
 1
L05
 72
hr
 868 1589 3429 0.4633 0.3566
MDA-MB-231 AZD7762
0.12
uM
LJP6
 2
L05
 72
hr
 868 1527 3652 0.4181 0.3132
MDA-MB-231 AZD7762
0.12
uM
LJP6
 3
L05
 72
hr
 868 1709 3587 0.4764 0.3922
MDA-MB-231 AZD7762
0.37
uM
LJP6
 1
L04
 72
hr
 868 1316 3429 0.3837 0.2335
MDA-MB-231 AZD7762
0.37
uM
LJP6
 2
L04
 72
hr
 868 1435 3652 0.3929 0.2744
MDA-MB-231 AZD7762
0.37
uM
LJP6
 3
L04
 72
hr
 868 1303 3587 0.3632 0.2194
MDA-MB-231 AZD7762
1.11
uM
LJP6
 1
L03
 72
hr
 868 839 3429 0.2446 -0.0171
MDA-MB-231 AZD7762
1.11
uM
LJP6
 2
L03
 72
hr
 868 808 3652 0.2213 -0.0340
MDA-MB-231 AZD7762
1.11
uM
LJP6
 3
L03
 72
hr
 868 910 3587 0.2537 0.0233