LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
SK-BR-3
LJP5
 3
N23
 72
hr
 1476 3241 3796 0.8537 0.7807
SK-BR-3
LJP5
 3
N24
 72
hr
 1476 2639 3796 0.6951 0.5314
MDA-MB-231 Seliciclib
0.04
uM
LJP5
 1
J06
 72
hr
 868 3512 3286 1.0687 1.0704
MDA-MB-231 Seliciclib
0.04
uM
LJP5
 2
J06
 72
hr
 868 3827 3505 1.0917 1.0891
MDA-MB-231 Seliciclib
0.04
uM
LJP5
 3
J06
 72
hr
 868 3570 3440 1.0377 1.0376
MDA-MB-231 Seliciclib
0.12
uM
LJP5
 1
J05
 72
hr
 868 3289 3286 1.0008 1.0009
MDA-MB-231 Seliciclib
0.12
uM
LJP5
 2
J05
 72
hr
 868 3639 3505 1.0381 1.0375
MDA-MB-231 Seliciclib
0.12
uM
LJP5
 3
J05
 72
hr
 868 3210 3440 0.9331 0.9315
MDA-MB-231 Seliciclib
0.37
uM
LJP5
 1
J04
 72
hr
 868 3016 3286 0.9178 0.9126
MDA-MB-231 Seliciclib
0.37
uM
LJP5
 2
J04
 72
hr
 868 3136 3505 0.8946 0.8924
MDA-MB-231 Seliciclib
0.37
uM
LJP5
 3
J04
 72
hr
 868 3031 3440 0.8810 0.8765
MDA-MB-231 Seliciclib
1.11
uM
LJP5
 1
J03
 72
hr
 868 2973 3286 0.9047 0.8983
MDA-MB-231 Seliciclib
1.11
uM
LJP5
 2
J03
 72
hr
 868 2878 3505 0.8210 0.8134
MDA-MB-231 Seliciclib
1.11
uM
LJP5
 3
J03
 72
hr
 868 2927 3440 0.8508 0.8438
MDA-MB-231 Seliciclib
3.33
uM
LJP5
 1
J02
 72
hr
 868 2594 3286 0.7893 0.7682
MDA-MB-231 Seliciclib
3.33
uM
LJP5
 2
J02
 72
hr
 868 2581 3505 0.7363 0.7179
MDA-MB-231 Seliciclib
3.33
uM
LJP5
 3
J02
 72
hr
 868 2699 3440 0.7845 0.7700
MDA-MB-231 Seliciclib
10
uM
LJP5
 1
J01
 72
hr
 868 1604 3286 0.4881 0.3767
MDA-MB-231 Seliciclib
10
uM
LJP5
 2
J01
 72
hr
 868 1457 3505 0.4156 0.2932
MDA-MB-231 Seliciclib
10
uM
LJP5
 3
J01
 72
hr
 868 1461 3440 0.4247 0.2996
MDA-MB-231 AT-7519
0.04
uM
LJP6
 1
K06
 72
hr
 868 2847 3429 0.8301 0.8207
MDA-MB-231 AT-7519
0.04
uM
LJP6
 2
K06
 72
hr
 868 3217 3652 0.8809 0.8813
MDA-MB-231 AT-7519
0.04
uM
LJP6
 3
K06
 72
hr
 868 3457 3587 0.9637 0.9642
MDA-MB-231 AT-7519
0.12
uM
LJP6
 1
K05
 72
hr
 868 2251 3429 0.6563 0.6172
MDA-MB-231 AT-7519
0.12
uM
LJP6
 2
K05
 72
hr
 868 2198 3652 0.6019 0.5655