LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
SK-BR-3 Radicicol
3.33
uM
LJP6
3
K08
72
hr
1476 1485 3734 0.3977 0.0042
SK-BR-3 Radicicol
3.33
uM
LJP5
1
K08
72
hr
1476 1668 3788 0.4403 0.0937
SK-BR-3 Radicicol
3.33
uM
LJP5
2
K08
72
hr
1476 1497 3731 0.4012 0.0103
SK-BR-3 Radicicol
3.33
uM
LJP5
3
K08
72
hr
1476 1560 3796 0.4109 0.0411
SK-BR-3 Radicicol
10
uM
LJP6
1
K07
72
hr
1476 1350 3413 0.3955 -0.0715
SK-BR-3 Radicicol
10
uM
LJP6
2
K07
72
hr
1476 904 3783 0.2389 -0.3034
SK-BR-3 Radicicol
10
uM
LJP6
3
K07
72
hr
1476 1118 3734 0.2994 -0.1877
SK-BR-3 Radicicol
10
uM
LJP5
1
K07
72
hr
1476 1199 3788 0.3165 -0.1421
SK-BR-3 Radicicol
10
uM
LJP5
2
K07
72
hr
1476 1176 3731 0.3152 -0.1566
SK-BR-3 Radicicol
10
uM
LJP5
3
K07
72
hr
1476 1266 3796 0.3335 -0.1069
SK-BR-3 Withaferin A
0.04
uM
LJP6
1
G18
72
hr
1476 3453 3413 1.0116 1.0192
SK-BR-3 Withaferin A
0.04
uM
LJP6
2
G18
72
hr
1476 3655 3783 0.9660 0.9497
SK-BR-3 Withaferin A
0.04
uM
LJP6
3
G18
72
hr
1476 4214 3734 1.1285 1.1891
SK-BR-3 Withaferin A
0.04
uM
LJP5
1
G18
72
hr
1476 3658 3788 0.9655 0.9490
SK-BR-3 Withaferin A
0.04
uM
LJP5
2
G18
72
hr
1476 3954 3731 1.0597 1.0886
SK-BR-3 Withaferin A
0.04
uM
LJP5
3
G18
72
hr
1476 3893 3796 1.0254 1.0371
SK-BR-3 Withaferin A
0.12
uM
LJP6
1
G17
72
hr
1476 2929 3413 0.8581 0.7622
SK-BR-3 Withaferin A
0.12
uM
LJP6
2
G17
72
hr
1476 3111 3783 0.8223 0.7315
SK-BR-3 Withaferin A
0.12
uM
LJP6
3
G17
72
hr
1476 3500 3734 0.9373 0.9056
SK-BR-3 Withaferin A
0.12
uM
LJP5
1
G17
72
hr
1476 3406 3788 0.8990 0.8493
SK-BR-3 Withaferin A
0.12
uM
LJP5
2
G17
72
hr
1476 3118 3731 0.8357 0.7487
SK-BR-3 Withaferin A
0.12
uM
LJP5
3
G17
72
hr
1476 3821 3796 1.0064 1.0094
SK-BR-3 Withaferin A
0.37
uM
LJP6
1
G16
72
hr
1476 1262 3413 0.3697 -0.1219
SK-BR-3 Withaferin A
0.37
uM
LJP6
2
G16
72
hr
1476 1603 3783 0.4237 0.0623
SK-BR-3 Withaferin A
0.37
uM
LJP6
3
G16
72
hr
1476 1388 3734 0.3717 -0.0452