LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 WZ-4-145
0.37
uM
LJP6
 3
J22
 72
hr
 868 2828 3587 0.7883 0.7806
MDA-MB-231 WZ-4-145
1.11
uM
LJP6
 1
J21
 72
hr
 868 2727 3429 0.7951 0.7815
MDA-MB-231 WZ-4-145
1.11
uM
LJP6
 2
J21
 72
hr
 868 2634 3652 0.7213 0.7083
MDA-MB-231 WZ-4-145
1.11
uM
LJP6
 3
J21
 72
hr
 868 2657 3587 0.7407 0.7272
MDA-MB-231 WZ-4-145
3.33
uM
LJP6
 1
J20
 72
hr
 868 2669 3429 0.7782 0.7623
MDA-MB-231 WZ-4-145
3.33
uM
LJP6
 2
J20
 72
hr
 868 2491 3652 0.6821 0.6629
MDA-MB-231 WZ-4-145
3.33
uM
LJP6
 3
J20
 72
hr
 868 2456 3587 0.6846 0.6621
MDA-MB-231 WZ-4-145
10
uM
LJP6
 1
J19
 72
hr
 868 1096 3429 0.3196 0.1248
MDA-MB-231 WZ-4-145
10
uM
LJP6
 2
J19
 72
hr
 868 946 3652 0.2590 0.0423
MDA-MB-231 WZ-4-145
10
uM
LJP6
 3
J19
 72
hr
 868 791 3587 0.2205 -0.0444
MDA-MB-231 WZ3105
0.04
uM
LJP5
 1
D24
 72
hr
 868 583 3286 0.1774 -0.1872
MDA-MB-231 WZ3105
0.04
uM
LJP5
 2
D24
 72
hr
 868 792 3505 0.2259 -0.0446
MDA-MB-231 WZ3105
0.04
uM
LJP5
 3
D24
 72
hr
 868 672 3440 0.1953 -0.1209
MDA-MB-231 WZ3105
0.12
uM
LJP5
 1
D23
 72
hr
 868 683 3286 0.2078 -0.1174
MDA-MB-231 WZ3105
0.12
uM
LJP5
 2
D23
 72
hr
 868 761 3505 0.2171 -0.0633
MDA-MB-231 WZ3105
0.12
uM
LJP5
 3
D23
 72
hr
 868 706 3440 0.2052 -0.0988
MDA-MB-231 WZ3105
0.37
uM
LJP5
 1
D22
 72
hr
 868 671 3286 0.2042 -0.1255
MDA-MB-231 WZ3105
0.37
uM
LJP5
 2
D22
 72
hr
 868 789 3505 0.2251 -0.0464
MDA-MB-231 WZ3105
0.37
uM
LJP5
 3
D22
 72
hr
 868 745 3440 0.2166 -0.0741
MDA-MB-231 WZ3105
1.11
uM
LJP5
 1
D21
 72
hr
 868 719 3286 0.2188 -0.0935
MDA-MB-231 WZ3105
1.11
uM
LJP5
 2
D21
 72
hr
 868 742 3505 0.2117 -0.0750
MDA-MB-231 WZ3105
1.11
uM
LJP5
 3
D21
 72
hr
 868 705 3440 0.2049 -0.0995
MDA-MB-231 WZ3105
3.33
uM
LJP5
 1
D20
 72
hr
 868 584 3286 0.1777 -0.1865
MDA-MB-231 WZ3105
3.33
uM
LJP5
 2
D20
 72
hr
 868 714 3505 0.2037 -0.0925
MDA-MB-231 WZ3105
3.33
uM
LJP5
 3
D20
 72
hr
 868 748 3440 0.2174 -0.0722