LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 NU7441
10
uM
LJP5
 3
C07
 72
hr
 868 1143 3440 0.3322 0.1485
MDA-MB-231 OSI-027
0.04
uM
LJP6
 1
E12
 72
hr
 868 3742 3429 1.0910 1.0899
MDA-MB-231 OSI-027
0.04
uM
LJP6
 2
E12
 72
hr
 868 3506 3652 0.9600 0.9610
MDA-MB-231 OSI-027
0.04
uM
LJP6
 3
E12
 72
hr
 868 3794 3587 1.0576 1.0555
MDA-MB-231 OSI-027
0.12
uM
LJP6
 1
E11
 72
hr
 868 3290 3429 0.9592 0.9585
MDA-MB-231 OSI-027
0.12
uM
LJP6
 2
E11
 72
hr
 868 3072 3652 0.8412 0.8399
MDA-MB-231 OSI-027
0.12
uM
LJP6
 3
E11
 72
hr
 868 3304 3587 0.9210 0.9212
MDA-MB-231 OSI-027
0.37
uM
LJP6
 1
E10
 72
hr
 868 3012 3429 0.8782 0.8731
MDA-MB-231 OSI-027
0.37
uM
LJP6
 2
E10
 72
hr
 868 2491 3652 0.6821 0.6629
MDA-MB-231 OSI-027
0.37
uM
LJP6
 3
E10
 72
hr
 868 3003 3587 0.8371 0.8336
MDA-MB-231 OSI-027
1.11
uM
LJP6
 1
E09
 72
hr
 868 2601 3429 0.7584 0.7395
MDA-MB-231 OSI-027
1.11
uM
LJP6
 2
E09
 72
hr
 868 2499 3652 0.6843 0.6655
MDA-MB-231 OSI-027
1.11
uM
LJP6
 3
E09
 72
hr
 868 2482 3587 0.6919 0.6706
MDA-MB-231 OSI-027
3.33
uM
LJP6
 1
E08
 72
hr
 868 2277 3429 0.6639 0.6266
MDA-MB-231 OSI-027
3.33
uM
LJP6
 2
E08
 72
hr
 868 2380 3652 0.6517 0.6267
MDA-MB-231 OSI-027
3.33
uM
LJP6
 3
E08
 72
hr
 868 2131 3587 0.5940 0.5507
MDA-MB-231 OSI-027
10
uM
LJP6
 1
E07
 72
hr
 868 1540 3429 0.4490 0.3353
MDA-MB-231 OSI-027
10
uM
LJP6
 2
E07
 72
hr
 868 1692 3652 0.4633 0.3798
MDA-MB-231 OSI-027
10
uM
LJP6
 3
E07
 72
hr
 868 1738 3587 0.4845 0.4037
MDA-MB-231 WYE-125132
0.04
uM
LJP6
 1
L12
 72
hr
 868 2300 3429 0.6706 0.6349
MDA-MB-231 WYE-125132
0.04
uM
LJP6
 2
L12
 72
hr
 868 2205 3652 0.6038 0.5679
MDA-MB-231 WYE-125132
0.04
uM
LJP6
 3
L12
 72
hr
 868 2316 3587 0.6456 0.6151
MDA-MB-231 WYE-125132
0.12
uM
LJP6
 1
L11
 72
hr
 868 1859 3429 0.5420 0.4684
MDA-MB-231 WYE-125132
0.12
uM
LJP6
 2
L11
 72
hr
 868 2147 3652 0.5879 0.5479
MDA-MB-231 WYE-125132
0.12
uM
LJP6
 3
L11
 72
hr
 868 2219 3587 0.6186 0.5817