LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 WYE-125132
0.37
uM
LJP6
 1
L10
 72
hr
 868 1758 3429 0.5126 0.4276
MDA-MB-231 WYE-125132
0.37
uM
LJP6
 2
L10
 72
hr
 868 1913 3652 0.5238 0.4640
MDA-MB-231 WYE-125132
0.37
uM
LJP6
 3
L10
 72
hr
 868 1948 3587 0.5430 0.4842
MDA-MB-231 WYE-125132
1.11
uM
LJP6
 1
L09
 72
hr
 868 1648 3429 0.4805 0.3818
MDA-MB-231 WYE-125132
1.11
uM
LJP6
 2
L09
 72
hr
 868 1783 3652 0.4882 0.4152
MDA-MB-231 WYE-125132
1.11
uM
LJP6
 3
L09
 72
hr
 868 1899 3587 0.5294 0.4658
MDA-MB-231 WYE-125132
3.33
uM
LJP6
 1
L08
 72
hr
 868 1527 3429 0.4452 0.3296
MDA-MB-231 WYE-125132
3.33
uM
LJP6
 2
L08
 72
hr
 868 1728 3652 0.4732 0.3939
MDA-MB-231 WYE-125132
3.33
uM
LJP6
 3
L08
 72
hr
 868 1597 3587 0.4452 0.3469
MDA-MB-231 WYE-125132
10
uM
LJP6
 1
L07
 72
hr
 868 1270 3429 0.3703 0.2116
MDA-MB-231 WYE-125132
10
uM
LJP6
 2
L07
 72
hr
 868 1454 3652 0.3981 0.2825
MDA-MB-231 WYE-125132
10
uM
LJP6
 3
L07
 72
hr
 868 1435 3587 0.4000 0.2783
MDA-MB-231 Barasertib
0.04
uM
LJP5
 1
D12
 72
hr
 868 1375 3286 0.4184 0.2706
MDA-MB-231 Barasertib
0.04
uM
LJP5
 2
D12
 72
hr
 868 1365 3505 0.3894 0.2520
MDA-MB-231 Barasertib
0.04
uM
LJP5
 3
D12
 72
hr
 868 1521 3440 0.4421 0.3262
MDA-MB-231 Barasertib
0.12
uM
LJP5
 1
D11
 72
hr
 868 1355 3286 0.4123 0.2609
MDA-MB-231 Barasertib
0.12
uM
LJP5
 2
D11
 72
hr
 868 1187 3505 0.3386 0.1681
MDA-MB-231 Barasertib
0.12
uM
LJP5
 3
D11
 72
hr
 868 1295 3440 0.3764 0.2230
MDA-MB-231 Barasertib
0.37
uM
LJP5
 1
D10
 72
hr
 868 1268 3286 0.3859 0.2181
MDA-MB-231 Barasertib
0.37
uM
LJP5
 2
D10
 72
hr
 868 1202 3505 0.3429 0.1754
MDA-MB-231 Barasertib
0.37
uM
LJP5
 3
D10
 72
hr
 868 1264 3440 0.3674 0.2082
MDA-MB-231 Barasertib
1.11
uM
LJP5
 1
D09
 72
hr
 868 1300 3286 0.3956 0.2340
MDA-MB-231 Barasertib
1.11
uM
LJP5
 2
D09
 72
hr
 868 1146 3505 0.3269 0.1479
MDA-MB-231 Barasertib
1.11
uM
LJP5
 3
D09
 72
hr
 868 1218 3440 0.3540 0.1859
MDA-MB-231 Barasertib
3.33
uM
LJP5
 1
D08
 72
hr
 868 1268 3286 0.3859 0.2181