LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 CGP60474
10
uM
LJP6
 2
G01
 72
hr
 868 456 3652 0.1249 -0.2670
MDA-MB-231 CGP60474
10
uM
LJP6
 3
G01
 72
hr
 868 585 3587 0.1631 -0.1754
MDA-MB-231 CGP60474
10
uM
LJP5
 1
F01
 72
hr
 868 566 3286 0.1722 -0.1997
MDA-MB-231 CGP60474
10
uM
LJP5
 2
F01
 72
hr
 868 593 3505 0.1692 -0.1724
MDA-MB-231 CGP60474
10
uM
LJP5
 3
F01
 72
hr
 868 601 3440 0.1747 -0.1690
MDA-MB-231 PD173074
0.04
uM
LJP6
 1
I12
 72
hr
 868 3982 3429 1.1610 1.1564
MDA-MB-231 PD173074
0.04
uM
LJP6
 2
I12
 72
hr
 868 4166 3652 1.1407 1.1312
MDA-MB-231 PD173074
0.04
uM
LJP6
 3
I12
 72
hr
 868 4106 3587 1.1446 1.1364
MDA-MB-231 PD173074
0.12
uM
LJP6
 1
I11
 72
hr
 868 3890 3429 1.1342 1.1312
MDA-MB-231 PD173074
0.12
uM
LJP6
 2
I11
 72
hr
 868 3858 3652 1.0564 1.0537
MDA-MB-231 PD173074
0.12
uM
LJP6
 3
I11
 72
hr
 868 4009 3587 1.1176 1.1116
MDA-MB-231 PD173074
0.37
uM
LJP6
 1
I10
 72
hr
 868 3614 3429 1.0537 1.0535
MDA-MB-231 PD173074
0.37
uM
LJP6
 2
I10
 72
hr
 868 3547 3652 0.9713 0.9721
MDA-MB-231 PD173074
0.37
uM
LJP6
 3
I10
 72
hr
 868 3618 3587 1.0086 1.0083
MDA-MB-231 PD173074
1.11
uM
LJP6
 1
I09
 72
hr
 868 3201 3429 0.9333 0.9315
MDA-MB-231 PD173074
1.11
uM
LJP6
 2
I09
 72
hr
 868 3952 3652 1.0821 1.0776
MDA-MB-231 PD173074
1.11
uM
LJP6
 3
I09
 72
hr
 868 3782 3587 1.0543 1.0523
MDA-MB-231 PD173074
3.33
uM
LJP6
 1
I08
 72
hr
 868 3544 3429 1.0333 1.0333
MDA-MB-231 PD173074
3.33
uM
LJP6
 2
I08
 72
hr
 868 3642 3652 0.9973 0.9974
MDA-MB-231 PD173074
3.33
uM
LJP6
 3
I08
 72
hr
 868 3770 3587 1.0509 1.0491
MDA-MB-231 PD173074
10
uM
LJP6
 1
I07
 72
hr
 868 1188 3429 0.3464 0.1715
MDA-MB-231 PD173074
10
uM
LJP6
 2
I07
 72
hr
 868 1347 3652 0.3688 0.2361
MDA-MB-231 PD173074
10
uM
LJP6
 3
I07
 72
hr
 868 1285 3587 0.3582 0.2112
MDA-MB-231 Crizotinib
0.04
uM
LJP5
 1
A24
 72
hr
 868 2398 3286 0.7297 0.6973
MDA-MB-231 Crizotinib
0.04
uM
LJP5
 2
A24
 72
hr
 868 2728 3505 0.7782 0.7658