LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 CP724714
10
uM
LJP5
 1
A07
 72
hr
 868 2441 3286 0.7428 0.7131
MDA-MB-231 CP724714
10
uM
LJP5
 2
A07
 72
hr
 868 2070 3505 0.5905 0.5396
MDA-MB-231 CP724714
10
uM
LJP5
 3
A07
 72
hr
 868 2476 3440 0.7197 0.6948
MDA-MB-231 Alvocidib
0.04
uM
LJP6
 1
A18
 72
hr
 868 1231 3429 0.3589 0.1927
MDA-MB-231 Alvocidib
0.04
uM
LJP6
 2
A18
 72
hr
 868 1272 3652 0.3483 0.2024
MDA-MB-231 Alvocidib
0.04
uM
LJP6
 3
A18
 72
hr
 868 1209 3587 0.3370 0.1756
MDA-MB-231 Alvocidib
0.12
uM
LJP6
 1
A17
 72
hr
 868 622 3429 0.1814 -0.1548
MDA-MB-231 Alvocidib
0.12
uM
LJP6
 2
A17
 72
hr
 868 610 3652 0.1670 -0.1565
MDA-MB-231 Alvocidib
0.12
uM
LJP6
 3
A17
 72
hr
 868 675 3587 0.1882 -0.1157
MDA-MB-231 Alvocidib
0.37
uM
LJP6
 1
A16
 72
hr
 868 620 3429 0.1808 -0.1562
MDA-MB-231 Alvocidib
0.37
uM
LJP6
 2
A16
 72
hr
 868 597 3652 0.1635 -0.1653
MDA-MB-231 Alvocidib
0.37
uM
LJP6
 3
A16
 72
hr
 868 616 3587 0.1717 -0.1543
MDA-MB-231 Alvocidib
1.11
uM
LJP6
 1
A15
 72
hr
 868 700 3429 0.2041 -0.1029
MDA-MB-231 Alvocidib
1.11
uM
LJP6
 2
A15
 72
hr
 868 661 3652 0.1810 -0.1232
MDA-MB-231 Alvocidib
1.11
uM
LJP6
 3
A15
 72
hr
 868 616 3587 0.1717 -0.1543
MDA-MB-231 Alvocidib
3.33
uM
LJP6
 1
A14
 72
hr
 868 700 3429 0.2041 -0.1029
MDA-MB-231 Alvocidib
3.33
uM
LJP6
 2
A14
 72
hr
 868 579 3652 0.1585 -0.1775
MDA-MB-231 Alvocidib
3.33
uM
LJP6
 3
A14
 72
hr
 868 557 3587 0.1553 -0.1949
MDA-MB-231 Alvocidib
10
uM
LJP6
 1
A13
 72
hr
 868 743 3429 0.2166 -0.0755
MDA-MB-231 Alvocidib
10
uM
LJP6
 2
A13
 72
hr
 868 611 3652 0.1673 -0.1559
MDA-MB-231 Alvocidib
10
uM
LJP6
 3
A13
 72
hr
 868 648 3587 0.1806 -0.1331
MDA-MB-231 GW843682X
0.04
uM
LJP6
 1
B18
 72
hr
 868 3210 3429 0.9359 0.9343
MDA-MB-231 GW843682X
0.04
uM
LJP6
 2
B18
 72
hr
 868 2833 3652 0.7757 0.7694
MDA-MB-231 GW843682X
0.04
uM
LJP6
 3
B18
 72
hr
 868 2760 3587 0.7694 0.7596
MDA-MB-231 GW843682X
0.12
uM
LJP6
 1
B17
 72
hr
 868 2701 3429 0.7875 0.7729