LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Crizotinib
0.04
uM
LJP5
 3
A24
 72
hr
 868 2323 3440 0.6752 0.6413
MDA-MB-231 Crizotinib
0.12
uM
LJP5
 1
A23
 72
hr
 868 2709 3286 0.8243 0.8086
MDA-MB-231 Crizotinib
0.12
uM
LJP5
 2
A23
 72
hr
 868 2839 3505 0.8099 0.8012
MDA-MB-231 Crizotinib
0.12
uM
LJP5
 3
A23
 72
hr
 868 2789 3440 0.8107 0.7995
MDA-MB-231 Crizotinib
0.37
uM
LJP5
 1
A22
 72
hr
 868 2318 3286 0.7054 0.6676
MDA-MB-231 Crizotinib
0.37
uM
LJP5
 2
A22
 72
hr
 868 2372 3505 0.6767 0.6474
MDA-MB-231 Crizotinib
0.37
uM
LJP5
 3
A22
 72
hr
 868 2510 3440 0.7296 0.7065
MDA-MB-231 Crizotinib
1.11
uM
LJP5
 1
A21
 72
hr
 868 1818 3286 0.5532 0.4694
MDA-MB-231 Crizotinib
1.11
uM
LJP5
 2
A21
 72
hr
 868 1804 3505 0.5146 0.4380
MDA-MB-231 Crizotinib
1.11
uM
LJP5
 3
A21
 72
hr
 868 1743 3440 0.5066 0.4203
MDA-MB-231 Crizotinib
3.33
uM
LJP5
 1
A20
 72
hr
 868 1116 3286 0.3396 0.1397
MDA-MB-231 Crizotinib
3.33
uM
LJP5
 2
A20
 72
hr
 868 1099 3505 0.3135 0.1243
MDA-MB-231 Crizotinib
3.33
uM
LJP5
 3
A20
 72
hr
 868 1185 3440 0.3445 0.1696
MDA-MB-231 Crizotinib
10
uM
LJP5
 1
A19
 72
hr
 868 1079 3286 0.3283 0.1199
MDA-MB-231 Crizotinib
10
uM
LJP5
 2
A19
 72
hr
 868 1097 3505 0.3129 0.1232
MDA-MB-231 Crizotinib
10
uM
LJP5
 3
A19
 72
hr
 868 1084 3440 0.3151 0.1183
MDA-MB-231 BMS345541
0.04
uM
LJP6
 1
D06
 72
hr
 868 3747 3429 1.0925 1.0913
MDA-MB-231 BMS345541
0.04
uM
LJP6
 2
D06
 72
hr
 868 3445 3652 0.9433 0.9445
MDA-MB-231 BMS345541
0.04
uM
LJP6
 3
D06
 72
hr
 868 3471 3587 0.9676 0.9681
MDA-MB-231 BMS345541
0.12
uM
LJP6
 1
D05
 72
hr
 868 4085 3429 1.1910 1.1844
MDA-MB-231 BMS345541
0.12
uM
LJP6
 2
D05
 72
hr
 868 3550 3652 0.9721 0.9729
MDA-MB-231 BMS345541
0.12
uM
LJP6
 3
D05
 72
hr
 868 3366 3587 0.9383 0.9388
MDA-MB-231 BMS345541
0.37
uM
LJP6
 1
D04
 72
hr
 868 3443 3429 1.0039 1.0039
MDA-MB-231 BMS345541
0.37
uM
LJP6
 2
D04
 72
hr
 868 3191 3652 0.8738 0.8739
MDA-MB-231 BMS345541
0.37
uM
LJP6
 3
D04
 72
hr
 868 3152 3587 0.8787 0.8775