LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 1
L18
 72
hr
 868 2979 3429 0.8686 0.8628
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 2
L18
 72
hr
 868 2884 3652 0.7897 0.7847
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 3
L18
 72
hr
 868 2743 3587 0.7646 0.7543
MDA-MB-231 Sirolimus
0.12
uM
LJP6
 1
L17
 72
hr
 868 2625 3429 0.7654 0.7476
MDA-MB-231 Sirolimus
0.12
uM
LJP6
 2
L17
 72
hr
 868 2749 3652 0.7527 0.7439
MDA-MB-231 Sirolimus
0.12
uM
LJP6
 3
L17
 72
hr
 868 2811 3587 0.7836 0.7754
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 1
L16
 72
hr
 868 2708 3429 0.7896 0.7753
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 2
L16
 72
hr
 868 3127 3652 0.8562 0.8557
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 3
L16
 72
hr
 868 3089 3587 0.8611 0.8591
MDA-MB-231 Sirolimus
1.11
uM
LJP6
 1
L15
 72
hr
 868 2591 3429 0.7554 0.7361
MDA-MB-231 Sirolimus
1.11
uM
LJP6
 2
L15
 72
hr
 868 2811 3652 0.7697 0.7627
MDA-MB-231 Sirolimus
1.11
uM
LJP6
 3
L15
 72
hr
 868 2741 3587 0.7641 0.7536
MDA-MB-231 Sirolimus
3.33
uM
LJP6
 1
L14
 72
hr
 868 2669 3429 0.7782 0.7623
MDA-MB-231 Sirolimus
3.33
uM
LJP6
 2
L14
 72
hr
 868 2885 3652 0.7900 0.7850
MDA-MB-231 Sirolimus
3.33
uM
LJP6
 3
L14
 72
hr
 868 2963 3587 0.8260 0.8217
MDA-MB-231 Sirolimus
10
uM
LJP6
 1
L13
 72
hr
 868 2799 3429 0.8161 0.8051
MDA-MB-231 Sirolimus
10
uM
LJP6
 2
L13
 72
hr
 868 3048 3652 0.8346 0.8330
MDA-MB-231 Sirolimus
10
uM
LJP6
 3
L13
 72
hr
 868 3144 3587 0.8764 0.8752
MDA-MB-231 ZSTK474
0.04
uM
LJP6
 1
M18
 72
hr
 868 3172 3429 0.9248 0.9227
MDA-MB-231 ZSTK474
0.04
uM
LJP6
 2
M18
 72
hr
 868 3592 3652 0.9836 0.9841
MDA-MB-231 ZSTK474
0.04
uM
LJP6
 3
M18
 72
hr
 868 3250 3587 0.9060 0.9058
MDA-MB-231 ZSTK474
0.12
uM
LJP6
 1
M17
 72
hr
 868 3108 3429 0.9062 0.9030
MDA-MB-231 ZSTK474
0.12
uM
LJP6
 2
M17
 72
hr
 868 3246 3652 0.8888 0.8895
MDA-MB-231 ZSTK474
0.12
uM
LJP6
 3
M17
 72
hr
 868 3054 3587 0.8513 0.8488
MDA-MB-231 ZSTK474
0.37
uM
LJP6
 1
M16
 72
hr
 868 2710 3429 0.7901 0.7759