LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Celastrol | 0.12 | uM | LJP6 | 3 | G11 | 72 | hr | 513 | 12164 | 10494 | 1.1591 | 1.0690 |
| MCF 10A | Sorafenib | 0.04 | uM | LJP6 | 3 | B12 | 72 | hr | 513 | 12106 | 10494 | 1.1535 | 1.0667 |
| MCF 10A | Celastrol | 0.04 | uM | LJP6 | 3 | G12 | 72 | hr | 513 | 11985 | 10494 | 1.1420 | 1.0619 |
| MCF 10A | Celastrol | 0.04 | uM | LJP6 | 2 | G12 | 72 | hr | 513 | 11882 | 10386 | 1.1439 | 1.0630 |
| MCF 10A | Celastrol | 0.12 | uM | LJP6 | 2 | G11 | 72 | hr | 513 | 11871 | 10386 | 1.1429 | 1.0625 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 2 | J12 | 72 | hr | 513 | 11790 | 10386 | 1.1351 | 1.0593 |
| MCF 10A | PLX-4720 | 1.11 | uM | LJP5 | 1 | K03 | 72 | hr | 513 | 11759 | 10254 | 1.1467 | 1.0644 |
| MCF 10A | PLX-4720 | 1.11 | uM | LJP5 | 2 | K03 | 72 | hr | 513 | 11743 | 10349 | 1.1346 | 1.0592 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 1 | J12 | 72 | hr | 513 | 11680 | 10537 | 1.1084 | 1.0478 |
| MCF 10A | KIN001-043 | 0.04 | uM | LJP6 | 3 | C12 | 72 | hr | 513 | 11620 | 10494 | 1.1072 | 1.0473 |
| MCF 10A | LJP6 | 3 | F12 | 72 | hr | 513 | 11605 | 10494 | 1.1058 | 1.0467 | |||
| MCF 10A | NU7441 | 0.04 | uM | LJP5 | 3 | C12 | 72 | hr | 513 | 11595 | 10483 | 1.1060 | 1.0468 |
| MCF 10A | CP724714 | 0.04 | uM | LJP5 | 3 | A12 | 72 | hr | 513 | 11568 | 10483 | 1.1034 | 1.0458 |
| MCF 10A | Sorafenib | 0.04 | uM | LJP6 | 1 | B12 | 72 | hr | 513 | 11484 | 10537 | 1.0898 | 1.0398 |
| MCF 10A | Nintedanib | 0.04 | uM | LJP6 | 1 | H06 | 72 | hr | 513 | 11473 | 10537 | 1.0887 | 1.0394 |
| MCF 10A | Imatinib | 3.33 | uM | LJP6 | 2 | N14 | 72 | hr | 513 | 11470 | 10386 | 1.1043 | 1.0463 |
| MCF 10A | PLX-4720 | 0.37 | uM | LJP5 | 2 | K04 | 72 | hr | 513 | 11400 | 10349 | 1.1015 | 1.0451 |
| MCF 10A | HG-6-64-01 | 0.04 | uM | LJP6 | 1 | M06 | 72 | hr | 513 | 11400 | 10537 | 1.0818 | 1.0364 |
| MCF 10A | Imatinib | 3.33 | uM | LJP6 | 1 | N14 | 72 | hr | 513 | 11387 | 10537 | 1.0806 | 1.0359 |
| MCF 10A | Linifanib | 0.12 | uM | LJP6 | 1 | J11 | 72 | hr | 513 | 11384 | 10537 | 1.0803 | 1.0357 |
| MCF 10A | Imatinib | 10 | uM | LJP6 | 1 | N13 | 72 | hr | 513 | 11371 | 10537 | 1.0791 | 1.0352 |
| MCF 10A | Foretinib | 0.04 | uM | LJP5 | 3 | H12 | 72 | hr | 513 | 11369 | 10483 | 1.0845 | 1.0376 |
| MCF 10A | LJP6 | 1 | J13 | 72 | hr | 513 | 11367 | 10537 | 1.0787 | 1.0350 | |||
| MCF 10A | Saracatinib | 0.04 | uM | LJP6 | 3 | D12 | 72 | hr | 513 | 11303 | 10494 | 1.0770 | 1.0344 |
| MCF 10A | Imatinib | 1.11 | uM | LJP6 | 2 | N15 | 72 | hr | 513 | 11283 | 10386 | 1.0863 | 1.0385 |