LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP6 | 3 | C19 | 72 | hr | 1476 | 455 | 3734 | 0.1219 | -0.5851 |
| SK-BR-3 | Geldanamycin | 10 | uM | LJP5 | 1 | O01 | 72 | hr | 1476 | 451 | 3788 | 0.1190 | -0.5821 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP6 | 1 | C19 | 72 | hr | 1476 | 540 | 3413 | 0.1582 | -0.5649 |
| MCF7 | AZD 5438 | 10 | uM | LJP6 | 2 | J01 | 72 | hr | 1235 | 319 | 4070 | 0.0784 | -0.5448 |
| MCF7 | Alvocidib | 10 | uM | LJP6 | 1 | A13 | 72 | hr | 1235 | 329 | 3974 | 0.0828 | -0.5438 |
| SK-BR-3 | QL-XII-47 | 10 | uM | LJP6 | 1 | O19 | 72 | hr | 1476 | 601 | 3413 | 0.1761 | -0.5247 |
| MCF7 | Mitoxantrone | 10 | uM | LJP6 | 2 | C19 | 72 | hr | 1235 | 344 | 4070 | 0.0845 | -0.5244 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP5 | 2 | C19 | 72 | hr | 1476 | 555 | 3731 | 0.1488 | -0.5190 |
| MCF7 | Mitoxantrone | 10 | uM | LJP5 | 3 | C19 | 72 | hr | 1235 | 332 | 4326 | 0.0767 | -0.5165 |
| MCF7 | CGP60474 | 10 | uM | LJP6 | 1 | G01 | 72 | hr | 1235 | 364 | 3974 | 0.0916 | -0.5156 |
| BT-20 | LDN-193189 | 10 | uM | LJP5 | 1 | G01 | 72 | hr | 1657 | 463 | 5624 | 0.0823 | -0.5151 |
| SK-BR-3 | LDN-193189 | 10 | uM | LJP5 | 1 | G01 | 72 | hr | 1476 | 555 | 3788 | 0.1465 | -0.5132 |
| MCF7 | AZD 5438 | 10 | uM | LJP6 | 1 | J01 | 72 | hr | 1235 | 380 | 3974 | 0.0956 | -0.5031 |
| SK-BR-3 | Geldanamycin | 10 | uM | LJP6 | 1 | O01 | 72 | hr | 1476 | 639 | 3413 | 0.1872 | -0.4999 |
| BT-20 | A443654 | 10 | uM | LJP6 | 2 | I19 | 72 | hr | 1657 | 524 | 5360 | 0.0978 | -0.4935 |
| MCF7 | CGP60474 | 10 | uM | LJP6 | 3 | G01 | 72 | hr | 1235 | 388 | 4126 | 0.0940 | -0.4861 |
| SK-BR-3 | CGP60474 | 10 | uM | LJP6 | 3 | G01 | 72 | hr | 1476 | 610 | 3734 | 0.1634 | -0.4835 |
| MCF7 | CGP60474 | 10 | uM | LJP6 | 2 | G01 | 72 | hr | 1235 | 398 | 4070 | 0.0978 | -0.4824 |
| SK-BR-3 | GSK1059615 | 10 | uM | LJP5 | 1 | E01 | 72 | hr | 1476 | 609 | 3788 | 0.1607 | -0.4788 |
| MCF7 | Canertinib | 10 | uM | LJP6 | 1 | H07 | 72 | hr | 1235 | 418 | 3974 | 0.1052 | -0.4742 |
| SK-BR-3 | Geldanamycin | 10 | uM | LJP5 | 2 | O01 | 72 | hr | 1476 | 630 | 3731 | 0.1689 | -0.4711 |
| MCF7 | Canertinib | 10 | uM | LJP6 | 2 | H07 | 72 | hr | 1235 | 419 | 4070 | 0.1029 | -0.4667 |
| SK-BR-3 | QL-XII-47 | 10 | uM | LJP6 | 2 | O19 | 72 | hr | 1476 | 630 | 3783 | 0.1665 | -0.4661 |
| SK-BR-3 | AZD 5438 | 10 | uM | LJP6 | 1 | J01 | 72 | hr | 1476 | 700 | 3413 | 0.2051 | -0.4608 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP6 | 2 | C19 | 72 | hr | 1476 | 639 | 3783 | 0.1689 | -0.4605 |