LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | LDN-193189 | 10 | uM | LJP5 | 3 | G01 | 72 | hr | 513 | 114 | 10483 | 0.0109 | -0.2923 |
| MCF 10A | LDN-193189 | 10 | uM | LJP5 | 1 | G01 | 72 | hr | 513 | 130 | 10254 | 0.0127 | -0.2723 |
| MCF 10A | LDN-193189 | 10 | uM | LJP5 | 2 | G01 | 72 | hr | 513 | 153 | 10349 | 0.0148 | -0.2437 |
| MCF 10A | Canertinib | 10 | uM | LJP6 | 2 | H07 | 72 | hr | 513 | 158 | 10386 | 0.0152 | -0.2378 |
| MCF 10A | Canertinib | 10 | uM | LJP6 | 3 | H07 | 72 | hr | 513 | 162 | 10494 | 0.0154 | -0.2327 |
| MCF 10A | Dasatinib | 10 | uM | LJP6 | 2 | I01 | 72 | hr | 513 | 198 | 10386 | 0.0191 | -0.1972 |
| MCF 10A | Dasatinib | 10 | uM | LJP6 | 1 | I01 | 72 | hr | 513 | 200 | 10537 | 0.0190 | -0.1945 |
| MCF 10A | HG-6-64-01 | 10 | uM | LJP6 | 1 | M01 | 72 | hr | 513 | 204 | 10537 | 0.0194 | -0.1908 |
| MCF 10A | Geldanamycin | 10 | uM | LJP6 | 2 | O01 | 72 | hr | 513 | 223 | 10386 | 0.0215 | -0.1748 |
| MCF 10A | Withaferin A | 10 | uM | LJP6 | 1 | G13 | 72 | hr | 513 | 236 | 10537 | 0.0224 | -0.1633 |
| MCF 10A | HG-6-64-01 | 10 | uM | LJP6 | 2 | M01 | 72 | hr | 513 | 241 | 10386 | 0.0232 | -0.1600 |
| MCF 10A | Withaferin A | 10 | uM | LJP5 | 1 | G13 | 72 | hr | 513 | 248 | 10254 | 0.0242 | -0.1550 |
| MCF 10A | Dasatinib | 10 | uM | LJP6 | 3 | I01 | 72 | hr | 513 | 253 | 10494 | 0.0241 | -0.1500 |
| MCF 10A | Dasatinib | 3.33 | uM | LJP6 | 2 | I02 | 72 | hr | 513 | 254 | 10386 | 0.0245 | -0.1497 |
| MCF 10A | GSK1059615 | 10 | uM | LJP5 | 1 | E01 | 72 | hr | 513 | 258 | 10254 | 0.0252 | -0.1472 |
| MCF 10A | GSK1059615 | 10 | uM | LJP6 | 2 | C01 | 72 | hr | 513 | 260 | 10386 | 0.0250 | -0.1451 |
| MCF 10A | Geldanamycin | 10 | uM | LJP5 | 3 | O01 | 72 | hr | 513 | 273 | 10483 | 0.0260 | -0.1351 |
| MCF 10A | GSK1059615 | 3.33 | uM | LJP5 | 1 | E02 | 72 | hr | 513 | 275 | 10254 | 0.0268 | -0.1345 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP6 | 3 | C19 | 72 | hr | 868 | 276 | 3587 | 0.0769 | -0.4287 |
| MCF 10A | GSK1059615 | 10 | uM | LJP5 | 3 | E01 | 72 | hr | 513 | 280 | 10483 | 0.0267 | -0.1300 |
| MCF 10A | Geldanamycin | 10 | uM | LJP6 | 1 | O01 | 72 | hr | 513 | 280 | 10537 | 0.0266 | -0.1298 |
| MCF 10A | Geldanamycin | 10 | uM | LJP6 | 3 | O01 | 72 | hr | 513 | 283 | 10494 | 0.0270 | -0.1279 |
| MCF 10A | Radicicol | 10 | uM | LJP5 | 3 | K07 | 72 | hr | 513 | 284 | 10483 | 0.0271 | -0.1272 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP6 | 1 | C19 | 72 | hr | 868 | 289 | 3429 | 0.0843 | -0.4259 |
| MCF 10A | Withaferin A | 3.33 | uM | LJP6 | 1 | G14 | 72 | hr | 513 | 290 | 10537 | 0.0275 | -0.1228 |