LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Celastrol | 1.11 | uM | LJP6 | 3 | G09 | 72 | hr | 1235 | 1392 | 4126 | 0.3373 | 0.0710 |
| MCF7 | Celastrol | 3.33 | uM | LJP6 | 1 | G08 | 72 | hr | 1235 | 861 | 3974 | 0.2167 | -0.1928 |
| MCF7 | Celastrol | 3.33 | uM | LJP6 | 2 | G08 | 72 | hr | 1235 | 752 | 4070 | 0.1848 | -0.2507 |
| MCF7 | Celastrol | 3.33 | uM | LJP6 | 3 | G08 | 72 | hr | 1235 | 879 | 4126 | 0.2130 | -0.1777 |
| MCF7 | Celastrol | 10 | uM | LJP6 | 1 | G07 | 72 | hr | 1235 | 1018 | 3974 | 0.2562 | -0.1085 |
| MCF7 | Celastrol | 10 | uM | LJP6 | 2 | G07 | 72 | hr | 1235 | 978 | 4070 | 0.2403 | -0.1270 |
| MCF7 | Celastrol | 10 | uM | LJP6 | 3 | G07 | 72 | hr | 1235 | 1157 | 4126 | 0.2804 | -0.0370 |
| MCF7 | SU11274 | 0.04 | uM | LJP5 | 1 | J12 | 72 | hr | 1235 | 4760 | 4119 | 1.1556 | 1.1736 |
| MCF7 | SU11274 | 0.04 | uM | LJP5 | 2 | J12 | 72 | hr | 1235 | 4653 | 4356 | 1.0681 | 1.0738 |
| MCF7 | SU11274 | 0.04 | uM | LJP5 | 3 | J12 | 72 | hr | 1235 | 5229 | 4326 | 1.2086 | 1.2209 |
| MCF7 | SU11274 | 0.12 | uM | LJP5 | 1 | J11 | 72 | hr | 1235 | 4847 | 4119 | 1.1767 | 1.1963 |
| MCF7 | SU11274 | 0.12 | uM | LJP5 | 2 | J11 | 72 | hr | 1235 | 4711 | 4356 | 1.0814 | 1.0880 |
| MCF7 | SU11274 | 0.12 | uM | LJP5 | 3 | J11 | 72 | hr | 1235 | 4796 | 4326 | 1.1085 | 1.1173 |
| MCF7 | SU11274 | 0.37 | uM | LJP5 | 1 | J10 | 72 | hr | 1235 | 4510 | 4119 | 1.0949 | 1.1071 |
| MCF7 | SU11274 | 0.37 | uM | LJP5 | 2 | J10 | 72 | hr | 1235 | 4606 | 4356 | 1.0573 | 1.0623 |
| MCF7 | SU11274 | 0.37 | uM | LJP5 | 3 | J10 | 72 | hr | 1235 | 4675 | 4326 | 1.0806 | 1.0876 |
| MCF7 | SU11274 | 1.11 | uM | LJP5 | 1 | J09 | 72 | hr | 1235 | 3773 | 4119 | 0.9160 | 0.9015 |
| MCF7 | SU11274 | 1.11 | uM | LJP5 | 2 | J09 | 72 | hr | 1235 | 3954 | 4356 | 0.9077 | 0.8962 |
| MCF7 | SU11274 | 1.11 | uM | LJP5 | 3 | J09 | 72 | hr | 1235 | 3963 | 4326 | 0.9160 | 0.9053 |
| MCF7 | SU11274 | 3.33 | uM | LJP5 | 1 | J08 | 72 | hr | 1235 | 2708 | 4119 | 0.6574 | 0.5710 |
| MCF7 | SU11274 | 3.33 | uM | LJP5 | 2 | J08 | 72 | hr | 1235 | 3400 | 4356 | 0.7805 | 0.7451 |
| MCF7 | SU11274 | 3.33 | uM | LJP5 | 3 | J08 | 72 | hr | 1235 | 3328 | 4326 | 0.7692 | 0.7299 |
| MCF7 | SU11274 | 10 | uM | LJP5 | 1 | J07 | 72 | hr | 1235 | 1521 | 4119 | 0.3693 | 0.1272 |
| MCF7 | SU11274 | 10 | uM | LJP5 | 2 | J07 | 72 | hr | 1235 | 1587 | 4356 | 0.3643 | 0.1477 |
| MCF7 | SU11274 | 10 | uM | LJP5 | 3 | J07 | 72 | hr | 1235 | 1620 | 4326 | 0.3744 | 0.1617 |