LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | PF431396 | 0.12 | uM | LJP5 | 2 | E11 | 72 | hr | 1235 | 2229 | 4356 | 0.5117 | 0.3835 |
| MCF7 | PF431396 | 0.12 | uM | LJP5 | 3 | E11 | 72 | hr | 1235 | 2118 | 4326 | 0.4896 | 0.3473 |
| MCF7 | PF431396 | 0.37 | uM | LJP5 | 1 | E10 | 72 | hr | 1235 | 1611 | 4119 | 0.3911 | 0.1651 |
| MCF7 | PF431396 | 0.37 | uM | LJP5 | 2 | E10 | 72 | hr | 1235 | 1676 | 4356 | 0.3847 | 0.1827 |
| MCF7 | PF431396 | 0.37 | uM | LJP5 | 3 | E10 | 72 | hr | 1235 | 1609 | 4326 | 0.3719 | 0.1573 |
| MCF7 | PF431396 | 1.11 | uM | LJP5 | 1 | E09 | 72 | hr | 1235 | 1404 | 4119 | 0.3408 | 0.0764 |
| MCF7 | PF431396 | 1.11 | uM | LJP5 | 2 | E09 | 72 | hr | 1235 | 1485 | 4356 | 0.3409 | 0.1065 |
| MCF7 | PF431396 | 1.11 | uM | LJP5 | 3 | E09 | 72 | hr | 1235 | 1421 | 4326 | 0.3285 | 0.0805 |
| MCF7 | PF431396 | 3.33 | uM | LJP5 | 1 | E08 | 72 | hr | 1235 | 1251 | 4119 | 0.3037 | 0.0073 |
| MCF7 | PF431396 | 3.33 | uM | LJP5 | 2 | E08 | 72 | hr | 1235 | 1159 | 4356 | 0.2661 | -0.0345 |
| MCF7 | PF431396 | 3.33 | uM | LJP5 | 3 | E08 | 72 | hr | 1235 | 1235 | 4326 | 0.2855 | -0.0002 |
| MCF7 | PF431396 | 10 | uM | LJP5 | 1 | E07 | 72 | hr | 1235 | 800 | 4119 | 0.1942 | -0.2213 |
| MCF7 | PF431396 | 10 | uM | LJP5 | 2 | E07 | 72 | hr | 1235 | 701 | 4356 | 0.1609 | -0.2678 |
| MCF7 | PF431396 | 10 | uM | LJP5 | 3 | E07 | 72 | hr | 1235 | 743 | 4326 | 0.1717 | -0.2451 |
| MCF7 | Celastrol | 0.04 | uM | LJP6 | 1 | G12 | 72 | hr | 1235 | 4491 | 3974 | 1.1301 | 1.1505 |
| MCF7 | Celastrol | 0.04 | uM | LJP6 | 2 | G12 | 72 | hr | 1235 | 4566 | 4070 | 1.1218 | 1.1382 |
| MCF7 | Celastrol | 0.04 | uM | LJP6 | 3 | G12 | 72 | hr | 1235 | 4427 | 4126 | 1.0729 | 1.0825 |
| MCF7 | Celastrol | 0.12 | uM | LJP6 | 1 | G11 | 72 | hr | 1235 | 3911 | 3974 | 0.9841 | 0.9811 |
| MCF7 | Celastrol | 0.12 | uM | LJP6 | 2 | G11 | 72 | hr | 1235 | 4030 | 4070 | 0.9901 | 0.9885 |
| MCF7 | Celastrol | 0.12 | uM | LJP6 | 3 | G11 | 72 | hr | 1235 | 4054 | 4126 | 0.9825 | 0.9798 |
| MCF7 | Celastrol | 0.37 | uM | LJP6 | 1 | G10 | 72 | hr | 1235 | 1982 | 3974 | 0.4987 | 0.3237 |
| MCF7 | Celastrol | 0.37 | uM | LJP6 | 2 | G10 | 72 | hr | 1235 | 1944 | 4070 | 0.4776 | 0.3016 |
| MCF7 | Celastrol | 0.37 | uM | LJP6 | 3 | G10 | 72 | hr | 1235 | 2217 | 4126 | 0.5373 | 0.3995 |
| MCF7 | Celastrol | 1.11 | uM | LJP6 | 1 | G09 | 72 | hr | 1235 | 1285 | 3974 | 0.3233 | 0.0236 |
| MCF7 | Celastrol | 1.11 | uM | LJP6 | 2 | G09 | 72 | hr | 1235 | 1263 | 4070 | 0.3103 | 0.0129 |