LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Momelotinib
0.04
uM
LJP5
 3
P12
 72
hr
 1235 4488 4326 1.0373 1.0410
MCF7 Momelotinib
0.12
uM
LJP5
 1
P11
 72
hr
 1235 3349 4119 0.8130 0.7754
MCF7 Momelotinib
0.12
uM
LJP5
 2
P11
 72
hr
 1235 3526 4356 0.8094 0.7804
MCF7 Momelotinib
0.12
uM
LJP5
 3
P11
 72
hr
 1235 3559 4326 0.8226 0.7953
MCF7 Momelotinib
0.37
uM
LJP5
 1
P10
 72
hr
 1235 3365 4119 0.8169 0.7802
MCF7 Momelotinib
0.37
uM
LJP5
 2
P10
 72
hr
 1235 3312 4356 0.7603 0.7201
MCF7 Momelotinib
0.37
uM
LJP5
 3
P10
 72
hr
 1235 3216 4326 0.7433 0.6974
MCF7 Momelotinib
1.11
uM
LJP5
 1
P09
 72
hr
 1235 2710 4119 0.6579 0.5717
MCF7 Momelotinib
1.11
uM
LJP5
 2
P09
 72
hr
 1235 2642 4356 0.6065 0.5191
MCF7 Momelotinib
1.11
uM
LJP5
 3
P09
 72
hr
 1235 3061 4326 0.7075 0.6517
MCF7 Momelotinib
3.33
uM
LJP5
 1
P08
 72
hr
 1235 1690 4119 0.4103 0.1976
MCF7 Momelotinib
3.33
uM
LJP5
 2
P08
 72
hr
 1235 1706 4356 0.3916 0.1943
MCF7 Momelotinib
3.33
uM
LJP5
 3
P08
 72
hr
 1235 1961 4326 0.4533 0.2912
MCF7 Momelotinib
10
uM
LJP5
 1
P07
 72
hr
 1235 1430 4119 0.3472 0.0878
MCF7 Momelotinib
10
uM
LJP5
 2
P07
 72
hr
 1235 1397 4356 0.3207 0.0700
MCF7 Momelotinib
10
uM
LJP5
 3
P07
 72
hr
 1235 1407 4326 0.3252 0.0746
MCF7 Fedratinib
0.04
uM
LJP5
 1
L06
 72
hr
 1235 3841 4119 0.9325 0.9211
MCF7 Fedratinib
0.04
uM
LJP5
 2
L06
 72
hr
 1235 5103 4356 1.1714 1.1818
MCF7 Fedratinib
0.04
uM
LJP5
 3
L06
 72
hr
 1235 4817 4326 1.1134 1.1224
MCF7 Fedratinib
0.12
uM
LJP5
 1
L05
 72
hr
 1235 4035 4119 0.9796 0.9764
MCF7 Fedratinib
0.12
uM
LJP5
 2
L05
 72
hr
 1235 4417 4356 1.0139 1.0153
MCF7 Fedratinib
0.12
uM
LJP5
 3
L05
 72
hr
 1235 4233 4326 0.9784 0.9760
MCF7 Fedratinib
0.37
uM
LJP5
 1
L04
 72
hr
 1235 3580 4119 0.8691 0.8448
MCF7 Fedratinib
0.37
uM
LJP5
 2
L04
 72
hr
 1235 3836 4356 0.8806 0.8649
MCF7 Fedratinib
0.37
uM
LJP5
 3
L04
 72
hr
 1235 3122 4326 0.7216 0.6698