LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Linsitinib | 3.33 | uM | LJP5 | 2 | O20 | 72 | hr | 1235 | 2102 | 4356 | 0.4825 | 0.3396 |
| MCF7 | Linsitinib | 3.33 | uM | LJP5 | 3 | O20 | 72 | hr | 1235 | 2472 | 4326 | 0.5714 | 0.4676 |
| MCF7 | Linsitinib | 10 | uM | LJP5 | 1 | O19 | 72 | hr | 1235 | 1740 | 4119 | 0.4224 | 0.2179 |
| MCF7 | Linsitinib | 10 | uM | LJP5 | 2 | O19 | 72 | hr | 1235 | 1848 | 4356 | 0.4242 | 0.2480 |
| MCF7 | Linsitinib | 10 | uM | LJP5 | 3 | O19 | 72 | hr | 1235 | 2017 | 4326 | 0.4662 | 0.3114 |
| MCF7 | Ruxolitinib | 0.04 | uM | LJP5 | 1 | O18 | 72 | hr | 1235 | 3867 | 4119 | 0.9388 | 0.9286 |
| MCF7 | Ruxolitinib | 0.04 | uM | LJP5 | 2 | O18 | 72 | hr | 1235 | 3730 | 4356 | 0.8562 | 0.8364 |
| MCF7 | Ruxolitinib | 0.04 | uM | LJP5 | 3 | O18 | 72 | hr | 1235 | 4077 | 4326 | 0.9424 | 0.9354 |
| MCF7 | Ruxolitinib | 0.12 | uM | LJP5 | 1 | O17 | 72 | hr | 1235 | 3742 | 4119 | 0.9084 | 0.8924 |
| MCF7 | Ruxolitinib | 0.12 | uM | LJP5 | 2 | O17 | 72 | hr | 1235 | 4132 | 4356 | 0.9485 | 0.9427 |
| MCF7 | Ruxolitinib | 0.12 | uM | LJP5 | 3 | O17 | 72 | hr | 1235 | 3998 | 4326 | 0.9241 | 0.9146 |
| MCF7 | Ruxolitinib | 0.37 | uM | LJP5 | 1 | O16 | 72 | hr | 1235 | 3642 | 4119 | 0.8842 | 0.8632 |
| MCF7 | Ruxolitinib | 0.37 | uM | LJP5 | 2 | O16 | 72 | hr | 1235 | 3897 | 4356 | 0.8946 | 0.8811 |
| MCF7 | Ruxolitinib | 0.37 | uM | LJP5 | 3 | O16 | 72 | hr | 1235 | 4382 | 4326 | 1.0128 | 1.0142 |
| MCF7 | Ruxolitinib | 1.11 | uM | LJP5 | 1 | O15 | 72 | hr | 1235 | 3991 | 4119 | 0.9689 | 0.9639 |
| MCF7 | Ruxolitinib | 1.11 | uM | LJP5 | 2 | O15 | 72 | hr | 1235 | 4316 | 4356 | 0.9908 | 0.9898 |
| MCF7 | Ruxolitinib | 1.11 | uM | LJP5 | 3 | O15 | 72 | hr | 1235 | 4601 | 4326 | 1.0635 | 1.0692 |
| MCF7 | Ruxolitinib | 3.33 | uM | LJP5 | 1 | O14 | 72 | hr | 1235 | 4038 | 4119 | 0.9803 | 0.9772 |
| MCF7 | Ruxolitinib | 3.33 | uM | LJP5 | 2 | O14 | 72 | hr | 1235 | 4567 | 4356 | 1.0484 | 1.0526 |
| MCF7 | Ruxolitinib | 3.33 | uM | LJP5 | 3 | O14 | 72 | hr | 1235 | 4590 | 4326 | 1.0609 | 1.0665 |
| MCF7 | Ruxolitinib | 10 | uM | LJP5 | 1 | O13 | 72 | hr | 1235 | 2940 | 4119 | 0.7137 | 0.6471 |
| MCF7 | Ruxolitinib | 10 | uM | LJP5 | 2 | O13 | 72 | hr | 1235 | 3122 | 4356 | 0.7167 | 0.6652 |
| MCF7 | Ruxolitinib | 10 | uM | LJP5 | 3 | O13 | 72 | hr | 1235 | 3490 | 4326 | 0.8067 | 0.7760 |
| MCF7 | Momelotinib | 0.04 | uM | LJP5 | 1 | P12 | 72 | hr | 1235 | 3439 | 4119 | 0.8349 | 0.8027 |
| MCF7 | Momelotinib | 0.04 | uM | LJP5 | 2 | P12 | 72 | hr | 1235 | 3883 | 4356 | 0.8914 | 0.8774 |