LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 GSK1904529A
0.37
uM
LJP6
 1
H22
 72
hr
 1235 2032 3974 0.5113 0.3434
MCF7 GSK1904529A
0.37
uM
LJP6
 2
H22
 72
hr
 1235 1884 4070 0.4629 0.2780
MCF7 GSK1904529A
0.37
uM
LJP6
 3
H22
 72
hr
 1235 1989 4126 0.4820 0.3149
MCF7 GSK1904529A
1.11
uM
LJP6
 1
H21
 72
hr
 1235 1928 3974 0.4851 0.3022
MCF7 GSK1904529A
1.11
uM
LJP6
 2
H21
 72
hr
 1235 1901 4070 0.4670 0.2847
MCF7 GSK1904529A
1.11
uM
LJP6
 3
H21
 72
hr
 1235 1883 4126 0.4563 0.2741
MCF7 GSK1904529A
3.33
uM
LJP6
 1
H20
 72
hr
 1235 1859 3974 0.4678 0.2743
MCF7 GSK1904529A
3.33
uM
LJP6
 2
H20
 72
hr
 1235 1866 4070 0.4584 0.2709
MCF7 GSK1904529A
3.33
uM
LJP6
 3
H20
 72
hr
 1235 2111 4126 0.5116 0.3606
MCF7 GSK1904529A
10
uM
LJP6
 1
H19
 72
hr
 1235 1556 3974 0.3915 0.1467
MCF7 GSK1904529A
10
uM
LJP6
 2
H19
 72
hr
 1235 1747 4070 0.4292 0.2232
MCF7 GSK1904529A
10
uM
LJP6
 3
H19
 72
hr
 1235 1925 4126 0.4665 0.2904
MCF7 Linsitinib
0.04
uM
LJP5
 1
O24
 72
hr
 1235 2970 4119 0.7210 0.6568
MCF7 Linsitinib
0.04
uM
LJP5
 2
O24
 72
hr
 1235 3703 4356 0.8500 0.8290
MCF7 Linsitinib
0.04
uM
LJP5
 3
O24
 72
hr
 1235 3058 4326 0.7068 0.6508
MCF7 Linsitinib
0.12
uM
LJP5
 1
O23
 72
hr
 1235 3415 4119 0.8290 0.7954
MCF7 Linsitinib
0.12
uM
LJP5
 2
O23
 72
hr
 1235 3145 4356 0.7220 0.6719
MCF7 Linsitinib
0.12
uM
LJP5
 3
O23
 72
hr
 1235 3245 4326 0.7500 0.7059
MCF7 Linsitinib
0.37
uM
LJP5
 1
O22
 72
hr
 1235 2435 4119 0.5911 0.4778
MCF7 Linsitinib
0.37
uM
LJP5
 2
O22
 72
hr
 1235 2497 4356 0.5732 0.4726
MCF7 Linsitinib
0.37
uM
LJP5
 3
O22
 72
hr
 1235 2272 4326 0.5251 0.4007
MCF7 Linsitinib
1.11
uM
LJP5
 1
O21
 72
hr
 1235 2235 4119 0.5426 0.4067
MCF7 Linsitinib
1.11
uM
LJP5
 2
O21
 72
hr
 1235 2082 4356 0.4779 0.3325
MCF7 Linsitinib
1.11
uM
LJP5
 3
O21
 72
hr
 1235 2437 4326 0.5633 0.4560
MCF7 Linsitinib
3.33
uM
LJP5
 1
O20
 72
hr
 1235 1988 4119 0.4826 0.3150