LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | TWS119 | 0.37 | uM | LJP5 | 3 | M04 | 72 | hr | 1235 | 3761 | 4326 | 0.8693 | 0.8509 |
| MCF7 | TWS119 | 1.11 | uM | LJP5 | 1 | M03 | 72 | hr | 1235 | 3820 | 4119 | 0.9274 | 0.9151 |
| MCF7 | TWS119 | 1.11 | uM | LJP5 | 2 | M03 | 72 | hr | 1235 | 4252 | 4356 | 0.9761 | 0.9735 |
| MCF7 | TWS119 | 1.11 | uM | LJP5 | 3 | M03 | 72 | hr | 1235 | 3550 | 4326 | 0.8205 | 0.7928 |
| MCF7 | TWS119 | 3.33 | uM | LJP5 | 1 | M02 | 72 | hr | 1235 | 2621 | 4119 | 0.6363 | 0.5418 |
| MCF7 | TWS119 | 3.33 | uM | LJP5 | 2 | M02 | 72 | hr | 1235 | 2678 | 4356 | 0.6147 | 0.5304 |
| MCF7 | TWS119 | 3.33 | uM | LJP5 | 3 | M02 | 72 | hr | 1235 | 2596 | 4326 | 0.6000 | 0.5078 |
| MCF7 | TWS119 | 10 | uM | LJP5 | 1 | M01 | 72 | hr | 1235 | 747 | 4119 | 0.1814 | -0.2514 |
| MCF7 | TWS119 | 10 | uM | LJP5 | 2 | M01 | 72 | hr | 1235 | 636 | 4356 | 0.1460 | -0.3059 |
| MCF7 | TWS119 | 10 | uM | LJP5 | 3 | M01 | 72 | hr | 1235 | 811 | 4326 | 0.1875 | -0.2077 |
| MCF7 | PF477736 | 0.04 | uM | LJP5 | 1 | J24 | 72 | hr | 1235 | 2562 | 4119 | 0.6220 | 0.5217 |
| MCF7 | PF477736 | 0.04 | uM | LJP5 | 2 | J24 | 72 | hr | 1235 | 2713 | 4356 | 0.6228 | 0.5414 |
| MCF7 | PF477736 | 0.04 | uM | LJP5 | 3 | J24 | 72 | hr | 1235 | 2532 | 4326 | 0.5852 | 0.4872 |
| MCF7 | PF477736 | 0.12 | uM | LJP5 | 1 | J23 | 72 | hr | 1235 | 1909 | 4119 | 0.4634 | 0.2847 |
| MCF7 | PF477736 | 0.12 | uM | LJP5 | 2 | J23 | 72 | hr | 1235 | 2379 | 4356 | 0.5461 | 0.4339 |
| MCF7 | PF477736 | 0.12 | uM | LJP5 | 3 | J23 | 72 | hr | 1235 | 2193 | 4326 | 0.5069 | 0.3735 |
| MCF7 | PF477736 | 0.37 | uM | LJP5 | 1 | J22 | 72 | hr | 1235 | 1935 | 4119 | 0.4698 | 0.2947 |
| MCF7 | PF477736 | 0.37 | uM | LJP5 | 2 | J22 | 72 | hr | 1235 | 2020 | 4356 | 0.4637 | 0.3106 |
| MCF7 | PF477736 | 0.37 | uM | LJP5 | 3 | J22 | 72 | hr | 1235 | 2156 | 4326 | 0.4983 | 0.3607 |
| MCF7 | PF477736 | 1.11 | uM | LJP5 | 1 | J21 | 72 | hr | 1235 | 1657 | 4119 | 0.4023 | 0.1841 |
| MCF7 | PF477736 | 1.11 | uM | LJP5 | 2 | J21 | 72 | hr | 1235 | 1801 | 4356 | 0.4134 | 0.2304 |
| MCF7 | PF477736 | 1.11 | uM | LJP5 | 3 | J21 | 72 | hr | 1235 | 1848 | 4326 | 0.4271 | 0.2495 |
| MCF7 | PF477736 | 3.33 | uM | LJP5 | 1 | J20 | 72 | hr | 1235 | 1584 | 4119 | 0.3845 | 0.1538 |
| MCF7 | PF477736 | 3.33 | uM | LJP5 | 2 | J20 | 72 | hr | 1235 | 1700 | 4356 | 0.3902 | 0.1920 |
| MCF7 | PF477736 | 3.33 | uM | LJP5 | 3 | J20 | 72 | hr | 1235 | 1738 | 4326 | 0.4017 | 0.2078 |