LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | PF477736 | 10 | uM | LJP5 | 1 | J19 | 72 | hr | 1235 | 1371 | 4119 | 0.3328 | 0.0618 |
| MCF7 | PF477736 | 10 | uM | LJP5 | 2 | J19 | 72 | hr | 1235 | 1388 | 4356 | 0.3186 | 0.0662 |
| MCF7 | PF477736 | 10 | uM | LJP5 | 3 | J19 | 72 | hr | 1235 | 1615 | 4326 | 0.3733 | 0.1597 |
| MCF7 | LDN-193189 | 0.04 | uM | LJP5 | 1 | G06 | 72 | hr | 1235 | 4265 | 4119 | 1.0354 | 1.0404 |
| MCF7 | LDN-193189 | 0.04 | uM | LJP5 | 2 | G06 | 72 | hr | 1235 | 4679 | 4356 | 1.0741 | 1.0802 |
| MCF7 | LDN-193189 | 0.04 | uM | LJP5 | 3 | G06 | 72 | hr | 1235 | 5439 | 4326 | 1.2572 | 1.2698 |
| MCF7 | LDN-193189 | 0.12 | uM | LJP5 | 1 | G05 | 72 | hr | 1235 | 4187 | 4119 | 1.0165 | 1.0189 |
| MCF7 | LDN-193189 | 0.12 | uM | LJP5 | 2 | G05 | 72 | hr | 1235 | 4517 | 4356 | 1.0369 | 1.0403 |
| MCF7 | LDN-193189 | 0.12 | uM | LJP5 | 3 | G05 | 72 | hr | 1235 | 4091 | 4326 | 0.9456 | 0.9391 |
| MCF7 | LDN-193189 | 0.37 | uM | LJP5 | 1 | G04 | 72 | hr | 1235 | 4455 | 4119 | 1.0815 | 1.0923 |
| MCF7 | LDN-193189 | 0.37 | uM | LJP5 | 2 | G04 | 72 | hr | 1235 | 4850 | 4356 | 1.1133 | 1.1217 |
| MCF7 | LDN-193189 | 0.37 | uM | LJP5 | 3 | G04 | 72 | hr | 1235 | 4587 | 4326 | 1.0602 | 1.0657 |
| MCF7 | LDN-193189 | 1.11 | uM | LJP5 | 1 | G03 | 72 | hr | 1235 | 3960 | 4119 | 0.9614 | 0.9551 |
| MCF7 | LDN-193189 | 1.11 | uM | LJP5 | 2 | G03 | 72 | hr | 1235 | 4102 | 4356 | 0.9416 | 0.9349 |
| MCF7 | LDN-193189 | 1.11 | uM | LJP5 | 3 | G03 | 72 | hr | 1235 | 3525 | 4326 | 0.8148 | 0.7858 |
| MCF7 | LDN-193189 | 3.33 | uM | LJP5 | 1 | G02 | 72 | hr | 1235 | 2105 | 4119 | 0.5110 | 0.3590 |
| MCF7 | LDN-193189 | 3.33 | uM | LJP5 | 2 | G02 | 72 | hr | 1235 | 2402 | 4356 | 0.5514 | 0.4415 |
| MCF7 | LDN-193189 | 3.33 | uM | LJP5 | 3 | G02 | 72 | hr | 1235 | 2066 | 4326 | 0.4775 | 0.3290 |
| MCF7 | LDN-193189 | 10 | uM | LJP5 | 1 | G01 | 72 | hr | 1235 | 639 | 4119 | 0.1551 | -0.3158 |
| MCF7 | LDN-193189 | 10 | uM | LJP5 | 2 | G01 | 72 | hr | 1235 | 557 | 4356 | 0.1279 | -0.3548 |
| MCF7 | LDN-193189 | 10 | uM | LJP5 | 3 | G01 | 72 | hr | 1235 | 523 | 4326 | 0.1209 | -0.3783 |
| MCF7 | PF431396 | 0.04 | uM | LJP5 | 1 | E12 | 72 | hr | 1235 | 3116 | 4119 | 0.7565 | 0.7032 |
| MCF7 | PF431396 | 0.04 | uM | LJP5 | 2 | E12 | 72 | hr | 1235 | 3269 | 4356 | 0.7504 | 0.7078 |
| MCF7 | PF431396 | 0.04 | uM | LJP5 | 3 | E12 | 72 | hr | 1235 | 3145 | 4326 | 0.7269 | 0.6766 |
| MCF7 | PF431396 | 0.12 | uM | LJP5 | 1 | E11 | 72 | hr | 1235 | 2205 | 4119 | 0.5353 | 0.3958 |