LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 WZ3105
10
uM
LJP5
 3
D19
 72
hr
 1235 614 4326 0.1419 -0.3207
MCF7 XMD11-50
0.04
uM
LJP6
 1
P12
 72
hr
 1235 3752 3974 0.9441 0.9329
MCF7 XMD11-50
0.04
uM
LJP6
 2
P12
 72
hr
 1235 3370 4070 0.8279 0.7921
MCF7 XMD11-50
0.04
uM
LJP6
 3
P12
 72
hr
 1235 3790 4126 0.9185 0.9046
MCF7 XMD11-50
0.12
uM
LJP6
 1
P11
 72
hr
 1235 3304 3974 0.8314 0.7925
MCF7 XMD11-50
0.12
uM
LJP6
 2
P11
 72
hr
 1235 2986 4070 0.7336 0.6704
MCF7 XMD11-50
0.12
uM
LJP6
 3
P11
 72
hr
 1235 3619 4126 0.8770 0.8547
MCF7 XMD11-50
0.37
uM
LJP6
 1
P10
 72
hr
 1235 3041 3974 0.7652 0.7064
MCF7 XMD11-50
0.37
uM
LJP6
 2
P10
 72
hr
 1235 2326 4070 0.5715 0.4446
MCF7 XMD11-50
0.37
uM
LJP6
 3
P10
 72
hr
 1235 2824 4126 0.6844 0.6083
MCF7 XMD11-50
1.11
uM
LJP6
 1
P09
 72
hr
 1235 2061 3974 0.5186 0.3548
MCF7 XMD11-50
1.11
uM
LJP6
 2
P09
 72
hr
 1235 1954 4070 0.4801 0.3054
MCF7 XMD11-50
1.11
uM
LJP6
 3
P09
 72
hr
 1235 2075 4126 0.5029 0.3472
MCF7 XMD11-50
3.33
uM
LJP6
 1
P08
 72
hr
 1235 1649 3974 0.4149 0.1869
MCF7 XMD11-50
3.33
uM
LJP6
 2
P08
 72
hr
 1235 1613 4070 0.3963 0.1677
MCF7 XMD11-50
3.33
uM
LJP6
 3
P08
 72
hr
 1235 1720 4126 0.4168 0.2095
MCF7 XMD11-50
10
uM
LJP6
 1
P07
 72
hr
 1235 1362 3974 0.3427 0.0596
MCF7 XMD11-50
10
uM
LJP6
 2
P07
 72
hr
 1235 1311 4070 0.3221 0.0351
MCF7 XMD11-50
10
uM
LJP6
 3
P07
 72
hr
 1235 1308 4126 0.3170 0.0334
MCF7 XMD11-85h
0.04
uM
LJP6
 1
P24
 72
hr
 1235 3145 3974 0.7914 0.7408
MCF7 XMD11-85h
0.04
uM
LJP6
 2
P24
 72
hr
 1235 3477 4070 0.8542 0.8250
MCF7 XMD11-85h
0.04
uM
LJP6
 3
P24
 72
hr
 1235 3335 4126 0.8082 0.7696
MCF7 XMD11-85h
0.12
uM
LJP6
 1
P23
 72
hr
 1235 3643 3974 0.9167 0.8994
MCF7 XMD11-85h
0.12
uM
LJP6
 2
P23
 72
hr
 1235 3315 4070 0.8144 0.7750
MCF7 XMD11-85h
0.12
uM
LJP6
 3
P23
 72
hr
 1235 3531 4126 0.8557 0.8287