LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 OSI-027
0.04
uM
LJP6
 2
E12
 72
hr
 1235 3916 4070 0.9621 0.9556
MCF7 OSI-027
0.04
uM
LJP6
 3
E12
 72
hr
 1235 3830 4126 0.9282 0.9161
MCF7 OSI-027
0.12
uM
LJP6
 1
E11
 72
hr
 1235 2811 3974 0.7073 0.6286
MCF7 OSI-027
0.12
uM
LJP6
 2
E11
 72
hr
 1235 3194 4070 0.7847 0.7371
MCF7 OSI-027
0.12
uM
LJP6
 3
E11
 72
hr
 1235 3053 4126 0.7399 0.6820
MCF7 OSI-027
0.37
uM
LJP6
 1
E10
 72
hr
 1235 1860 3974 0.4680 0.2748
MCF7 OSI-027
0.37
uM
LJP6
 2
E10
 72
hr
 1235 2218 4070 0.5449 0.4052
MCF7 OSI-027
0.37
uM
LJP6
 3
E10
 72
hr
 1235 2135 4126 0.5174 0.3695
MCF7 OSI-027
1.11
uM
LJP6
 1
E09
 72
hr
 1235 2112 3974 0.5314 0.3745
MCF7 OSI-027
1.11
uM
LJP6
 2
E09
 72
hr
 1235 1817 4070 0.4464 0.2514
MCF7 OSI-027
1.11
uM
LJP6
 3
E09
 72
hr
 1235 1993 4126 0.4830 0.3164
MCF7 OSI-027
3.33
uM
LJP6
 1
E08
 72
hr
 1235 1911 3974 0.4809 0.2954
MCF7 OSI-027
3.33
uM
LJP6
 2
E08
 72
hr
 1235 1694 4070 0.4162 0.2015
MCF7 OSI-027
3.33
uM
LJP6
 3
E08
 72
hr
 1235 1762 4126 0.4270 0.2264
MCF7 OSI-027
10
uM
LJP6
 1
E07
 72
hr
 1235 1517 3974 0.3817 0.1296
MCF7 OSI-027
10
uM
LJP6
 2
E07
 72
hr
 1235 1650 4070 0.4054 0.1832
MCF7 OSI-027
10
uM
LJP6
 3
E07
 72
hr
 1235 1704 4126 0.4130 0.2030
MCF7 WYE-125132
0.04
uM
LJP6
 1
L12
 72
hr
 1235 1772 3974 0.4459 0.2386
MCF7 WYE-125132
0.04
uM
LJP6
 2
L12
 72
hr
 1235 1761 4070 0.4326 0.2289
MCF7 WYE-125132
0.04
uM
LJP6
 3
L12
 72
hr
 1235 1756 4126 0.4256 0.2240
MCF7 WYE-125132
0.12
uM
LJP6
 1
L11
 72
hr
 1235 1831 3974 0.4607 0.2629
MCF7 WYE-125132
0.12
uM
LJP6
 2
L11
 72
hr
 1235 1696 4070 0.4167 0.2023
MCF7 WYE-125132
0.12
uM
LJP6
 3
L11
 72
hr
 1235 1649 4126 0.3996 0.1806
MCF7 WYE-125132
0.37
uM
LJP6
 1
L10
 72
hr
 1235 1596 3974 0.4016 0.1641
MCF7 WYE-125132
0.37
uM
LJP6
 2
L10
 72
hr
 1235 1697 4070 0.4169 0.2027