LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 WYE-125132
0.37
uM
LJP6
 3
L10
 72
hr
 1235 1632 4126 0.3955 0.1735
MCF7 WYE-125132
1.11
uM
LJP6
 1
L09
 72
hr
 1235 1789 3974 0.4502 0.2457
MCF7 WYE-125132
1.11
uM
LJP6
 2
L09
 72
hr
 1235 1604 4070 0.3941 0.1639
MCF7 WYE-125132
1.11
uM
LJP6
 3
L09
 72
hr
 1235 1950 4126 0.4726 0.3000
MCF7 WYE-125132
3.33
uM
LJP6
 1
L08
 72
hr
 1235 1710 3974 0.4303 0.2127
MCF7 WYE-125132
3.33
uM
LJP6
 2
L08
 72
hr
 1235 1681 4070 0.4130 0.1961
MCF7 WYE-125132
3.33
uM
LJP6
 3
L08
 72
hr
 1235 1606 4126 0.3892 0.1628
MCF7 WYE-125132
10
uM
LJP6
 1
L07
 72
hr
 1235 1389 3974 0.3495 0.0720
MCF7 WYE-125132
10
uM
LJP6
 2
L07
 72
hr
 1235 1381 4070 0.3393 0.0669
MCF7 WYE-125132
10
uM
LJP6
 3
L07
 72
hr
 1235 1411 4126 0.3420 0.0794
MCF7 Barasertib
0.04
uM
LJP5
 1
D12
 72
hr
 1235 1920 4119 0.4661 0.2889
MCF7 Barasertib
0.04
uM
LJP5
 2
D12
 72
hr
 1235 1567 4356 0.3597 0.1397
MCF7 Barasertib
0.04
uM
LJP5
 3
D12
 72
hr
 1235 1710 4326 0.3953 0.1970
MCF7 Barasertib
0.12
uM
LJP5
 1
D11
 72
hr
 1235 1611 4119 0.3911 0.1651
MCF7 Barasertib
0.12
uM
LJP5
 2
D11
 72
hr
 1235 1578 4356 0.3622 0.1441
MCF7 Barasertib
0.12
uM
LJP5
 3
D11
 72
hr
 1235 1604 4326 0.3707 0.1554
MCF7 Barasertib
0.37
uM
LJP5
 1
D10
 72
hr
 1235 1612 4119 0.3913 0.1655
MCF7 Barasertib
0.37
uM
LJP5
 2
D10
 72
hr
 1235 1560 4356 0.3581 0.1369
MCF7 Barasertib
0.37
uM
LJP5
 3
D10
 72
hr
 1235 1683 4326 0.3890 0.1865
MCF7 Barasertib
1.11
uM
LJP5
 1
D09
 72
hr
 1235 1541 4119 0.3741 0.1357
MCF7 Barasertib
1.11
uM
LJP5
 2
D09
 72
hr
 1235 1517 4356 0.3482 0.1196
MCF7 Barasertib
1.11
uM
LJP5
 3
D09
 72
hr
 1235 1585 4326 0.3664 0.1478
MCF7 Barasertib
3.33
uM
LJP5
 1
D08
 72
hr
 1235 1630 4119 0.3957 0.1730
MCF7 Barasertib
3.33
uM
LJP5
 2
D08
 72
hr
 1235 1542 4356 0.3540 0.1297
MCF7 Barasertib
3.33
uM
LJP5
 3
D08
 72
hr
 1235 1633 4326 0.3775 0.1669