LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Barasertib | 10 | uM | LJP5 | 1 | D07 | 72 | hr | 1235 | 1503 | 4119 | 0.3649 | 0.1195 |
| MCF7 | Barasertib | 10 | uM | LJP5 | 2 | D07 | 72 | hr | 1235 | 1626 | 4356 | 0.3733 | 0.1631 |
| MCF7 | Barasertib | 10 | uM | LJP5 | 3 | D07 | 72 | hr | 1235 | 1521 | 4326 | 0.3516 | 0.1219 |
| MCF7 | Vemurafenib | 0.04 | uM | LJP5 | 1 | C18 | 72 | hr | 1235 | 4585 | 4119 | 1.1131 | 1.1272 |
| MCF7 | Vemurafenib | 0.04 | uM | LJP5 | 2 | C18 | 72 | hr | 1235 | 4325 | 4356 | 0.9928 | 0.9921 |
| MCF7 | Vemurafenib | 0.04 | uM | LJP5 | 3 | C18 | 72 | hr | 1235 | 3749 | 4326 | 0.8665 | 0.8477 |
| MCF7 | Vemurafenib | 0.12 | uM | LJP5 | 1 | C17 | 72 | hr | 1235 | 4431 | 4119 | 1.0757 | 1.0858 |
| MCF7 | Vemurafenib | 0.12 | uM | LJP5 | 2 | C17 | 72 | hr | 1235 | 4462 | 4356 | 1.0243 | 1.0266 |
| MCF7 | Vemurafenib | 0.12 | uM | LJP5 | 3 | C17 | 72 | hr | 1235 | 4390 | 4326 | 1.0147 | 1.0162 |
| MCF7 | Vemurafenib | 0.37 | uM | LJP5 | 1 | C16 | 72 | hr | 1235 | 4496 | 4119 | 1.0915 | 1.1033 |
| MCF7 | Vemurafenib | 0.37 | uM | LJP5 | 2 | C16 | 72 | hr | 1235 | 4101 | 4356 | 0.9414 | 0.9347 |
| MCF7 | Vemurafenib | 0.37 | uM | LJP5 | 3 | C16 | 72 | hr | 1235 | 4360 | 4326 | 1.0078 | 1.0086 |
| MCF7 | Vemurafenib | 1.11 | uM | LJP5 | 1 | C15 | 72 | hr | 1235 | 4237 | 4119 | 1.0286 | 1.0327 |
| MCF7 | Vemurafenib | 1.11 | uM | LJP5 | 2 | C15 | 72 | hr | 1235 | 4184 | 4356 | 0.9605 | 0.9561 |
| MCF7 | Vemurafenib | 1.11 | uM | LJP5 | 3 | C15 | 72 | hr | 1235 | 3982 | 4326 | 0.9204 | 0.9103 |
| MCF7 | Vemurafenib | 3.33 | uM | LJP5 | 1 | C14 | 72 | hr | 1235 | 4321 | 4119 | 1.0490 | 1.0558 |
| MCF7 | Vemurafenib | 3.33 | uM | LJP5 | 2 | C14 | 72 | hr | 1235 | 4092 | 4356 | 0.9393 | 0.9323 |
| MCF7 | Vemurafenib | 3.33 | uM | LJP5 | 3 | C14 | 72 | hr | 1235 | 4066 | 4326 | 0.9398 | 0.9325 |
| MCF7 | Vemurafenib | 10 | uM | LJP5 | 1 | C13 | 72 | hr | 1235 | 3598 | 4119 | 0.8735 | 0.8502 |
| MCF7 | Vemurafenib | 10 | uM | LJP5 | 2 | C13 | 72 | hr | 1235 | 3448 | 4356 | 0.7915 | 0.7586 |
| MCF7 | Vemurafenib | 10 | uM | LJP5 | 3 | C13 | 72 | hr | 1235 | 3412 | 4326 | 0.7886 | 0.7539 |
| MCF7 | Enzastaurin | 0.04 | uM | LJP5 | 1 | D18 | 72 | hr | 1235 | 4265 | 4119 | 1.0354 | 1.0404 |
| MCF7 | Enzastaurin | 0.04 | uM | LJP5 | 2 | D18 | 72 | hr | 1235 | 3868 | 4356 | 0.8879 | 0.8734 |
| MCF7 | Enzastaurin | 0.04 | uM | LJP5 | 3 | D18 | 72 | hr | 1235 | 3977 | 4326 | 0.9192 | 0.9090 |
| MCF7 | Enzastaurin | 0.12 | uM | LJP5 | 1 | D17 | 72 | hr | 1235 | 4361 | 4119 | 1.0587 | 1.0667 |