LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Enzastaurin
0.12
uM
LJP5
 2
D17
 72
hr
 1235 3879 4356 0.8904 0.8763
MCF7 Enzastaurin
0.12
uM
LJP5
 3
D17
 72
hr
 1235 4162 4326 0.9620 0.9576
MCF7 Enzastaurin
0.37
uM
LJP5
 1
D16
 72
hr
 1235 4423 4119 1.0737 1.0836
MCF7 Enzastaurin
0.37
uM
LJP5
 2
D16
 72
hr
 1235 4239 4356 0.9731 0.9702
MCF7 Enzastaurin
0.37
uM
LJP5
 3
D16
 72
hr
 1235 4395 4326 1.0158 1.0175
MCF7 Enzastaurin
1.11
uM
LJP5
 1
D15
 72
hr
 1235 4196 4119 1.0186 1.0214
MCF7 Enzastaurin
1.11
uM
LJP5
 2
D15
 72
hr
 1235 3514 4356 0.8067 0.7771
MCF7 Enzastaurin
1.11
uM
LJP5
 3
D15
 72
hr
 1235 4084 4326 0.9440 0.9372
MCF7 Enzastaurin
3.33
uM
LJP5
 1
D14
 72
hr
 1235 4008 4119 0.9730 0.9687
MCF7 Enzastaurin
3.33
uM
LJP5
 2
D14
 72
hr
 1235 3560 4356 0.8172 0.7898
MCF7 Enzastaurin
3.33
uM
LJP5
 3
D14
 72
hr
 1235 3635 4326 0.8402 0.8164
MCF7 Enzastaurin
10
uM
LJP5
 1
D13
 72
hr
 1235 2356 4119 0.5720 0.4500
MCF7 Enzastaurin
10
uM
LJP5
 2
D13
 72
hr
 1235 2309 4356 0.5300 0.4106
MCF7 Enzastaurin
10
uM
LJP5
 3
D13
 72
hr
 1235 2272 4326 0.5251 0.4007
MCF7 Palbociclib
0.04
uM
LJP6
 1
E18
 72
hr
 1235 2819 3974 0.7093 0.6314
MCF7 Palbociclib
0.04
uM
LJP6
 2
E18
 72
hr
 1235 2950 4070 0.7248 0.6587
MCF7 Palbociclib
0.04
uM
LJP6
 3
E18
 72
hr
 1235 3286 4126 0.7963 0.7546
MCF7 Palbociclib
0.12
uM
LJP6
 1
E17
 72
hr
 1235 2263 3974 0.5694 0.4320
MCF7 Palbociclib
0.12
uM
LJP6
 2
E17
 72
hr
 1235 2381 4070 0.5850 0.4644
MCF7 Palbociclib
0.12
uM
LJP6
 3
E17
 72
hr
 1235 2632 4126 0.6379 0.5445
MCF7 Palbociclib
0.37
uM
LJP6
 1
E16
 72
hr
 1235 1899 3974 0.4778 0.2905
MCF7 Palbociclib
0.37
uM
LJP6
 2
E16
 72
hr
 1235 2338 4070 0.5744 0.4490
MCF7 Palbociclib
0.37
uM
LJP6
 3
E16
 72
hr
 1235 2135 4126 0.5174 0.3695
MCF7 Palbociclib
1.11
uM
LJP6
 1
E15
 72
hr
 1235 1787 3974 0.4497 0.2448
MCF7 Palbociclib
1.11
uM
LJP6
 2
E15
 72
hr
 1235 1757 4070 0.4317 0.2272